Difference between revisions of "YML106W"

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'''Description of YML106W:''' Major orotate phosphoribosyltransferase (OPRTase) isozyme that catalyzes the fifth enzymatic step in de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate; minor OPRTase encoded by URA10<ref name='S000081430'>Umezu K, et al. (1971) Purification and properties of orotidine-5'-phosphate pyrophosphorylase and orotidine-5'-phosphate decarboxylase from baker's yeast. J Biochem 70(2):249-62 {{SGDpaper|S000081430}} PMID 5094209</ref><ref name='S000063561'>Schmidt R, et al. (1979) Purification and characterization of the hypoxanthine-guanine phosphoribosyltransferase from Saccharomyces cerevisiae. Eur J Biochem 93(2):355-61 {{SGDpaper|S000063561}} PMID 371963</ref><ref name='S000050796'>de Montigny J, et al. (1989) Structure and expression of the URA5 gene of Saccharomyces cerevisiae. Mol Gen Genet 215(3):455-62 {{SGDpaper|S000050796}} PMID 2651891</ref><ref name='S000048197'>de Montigny J, et al. (1990) Cloning and sequencing of URA10, a second gene encoding orotate phosphoribosyl transferase in Saccharomyces cerevisiae. Curr Genet 17(2):105-11
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'''Description of YML106W:''' Major orotate phosphoribosyltransferase (OPRTase) isozyme that catalyzes the fifth enzymatic step in de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate; minor OPRTase encoded by URA10<ref name='S000048197'>de Montigny J, et al. (1990) Cloning and sequencing of URA10, a second gene encoding orotate phosphoribosyl transferase in Saccharomyces cerevisiae. Curr Genet 17(2):105-11 {{SGDpaper|S000048197}} PMID 2182197</ref><ref name='S000050796'>de Montigny J, et al. (1989) Structure and expression of the URA5 gene of Saccharomyces cerevisiae. Mol Gen Genet 215(3):455-62 {{SGDpaper|S000050796}} PMID 2651891</ref><ref name='S000063561'>Schmidt R, et al. (1979) Purification and characterization of the hypoxanthine-guanine phosphoribosyltransferase from Saccharomyces cerevisiae. Eur J Biochem 93(2):355-61 {{SGDpaper|S000063561}} PMID 371963</ref><ref name='S000081430'>Umezu K, et al. (1971) Purification and properties of orotidine-5'-phosphate pyrophosphorylase and orotidine-5'-phosphate decarboxylase from baker's yeast. J Biochem 70(2):249-62
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  {{SGDpaper|S000081430}} PMID 5094209</ref>
 
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Revision as of 14:05, 31 March 2009

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Systematic name YML106W
Gene name URA5
Aliases PYR5
Feature type ORF, Verified
Coordinates Chr XIII:56773..57453
Primary SGDID S000004574


Description of YML106W: Major orotate phosphoribosyltransferase (OPRTase) isozyme that catalyzes the fifth enzymatic step in de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate; minor OPRTase encoded by URA10[1][2][3][4]




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References

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  1. de Montigny J, et al. (1990) Cloning and sequencing of URA10, a second gene encoding orotate phosphoribosyl transferase in Saccharomyces cerevisiae. Curr Genet 17(2):105-11 SGD PMID 2182197
  2. de Montigny J, et al. (1989) Structure and expression of the URA5 gene of Saccharomyces cerevisiae. Mol Gen Genet 215(3):455-62 SGD PMID 2651891
  3. Schmidt R, et al. (1979) Purification and characterization of the hypoxanthine-guanine phosphoribosyltransferase from Saccharomyces cerevisiae. Eur J Biochem 93(2):355-61 SGD PMID 371963
  4. Umezu K, et al. (1971) Purification and properties of orotidine-5'-phosphate pyrophosphorylase and orotidine-5'-phosphate decarboxylase from baker's yeast. J Biochem 70(2):249-62 SGD PMID 5094209

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