Difference between revisions of "YML061C"

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'''Description of YML061C:''' DNA helicase; exists in two forms; the nuclear form is involved in telomere formation and elongation; acts as a catalytic inhibitor of telomerase; the mitochondrial form is involved in repair and recombination of mitochondrial DNA<ref name='S000041506'>Ivessa AS, et al. (2000) The Saccharomyces Pif1p DNA helicase and the highly related Rrm3p have opposite effects on replication fork progression in ribosomal DNA. Cell 100(4):479-89 {{SGDpaper|S000041506}} PMID 10693764</ref><ref name='S000046554'>Foury F and Lahaye A (1987) Cloning and sequencing of the PIF gene involved in repair and recombination of yeast mitochondrial DNA. EMBO J 6(5):1441-9 {{SGDpaper|S000046554}} PMID 3038524</ref><ref name='S000055909'>Zhou J, et al. (2000) Pif1p helicase, a catalytic inhibitor of telomerase in yeast. Science 289(5480):771-4 {{SGDpaper|S000055909}} PMID 10926538</ref><ref name='S000123131'>Vega LR, et al. (2007) Sensitivity of yeast strains with long g-tails to levels of telomere-bound telomerase. PLoS Genet 3(6):e105
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'''Description of YML061C:''' DNA helicase; exists in two forms; the nuclear form is involved in telomere formation and elongation; acts as a catalytic inhibitor of telomerase; the mitochondrial form is involved in repair and recombination of mitochondrial DNA<ref name='S000046554'>Foury F and Lahaye A (1987) Cloning and sequencing of the PIF gene involved in repair and recombination of yeast mitochondrial DNA. EMBO J 6(5):1441-9 {{SGDpaper|S000046554}} PMID 3038524</ref><ref name='S000041506'>Ivessa AS, et al. (2000) The Saccharomyces Pif1p DNA helicase and the highly related Rrm3p have opposite effects on replication fork progression in ribosomal DNA. Cell 100(4):479-89 {{SGDpaper|S000041506}} PMID 10693764</ref><ref name='S000123131'>Vega LR, et al. (2007) Sensitivity of yeast strains with long g-tails to levels of telomere-bound telomerase. PLoS Genet 3(6):e105 {{SGDpaper|S000123131}} PMID 17590086</ref><ref name='S000055909'>Zhou J, et al. (2000) Pif1p helicase, a catalytic inhibitor of telomerase in yeast. Science 289(5480):771-4
  {{SGDpaper|S000123131}} PMID 17590086</ref>
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  {{SGDpaper|S000055909}} PMID 10926538</ref>
 
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Revision as of 14:05, 25 February 2010

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Systematic name YML061C
Gene name PIF1
Aliases TST1
Feature type ORF, Verified
Coordinates Chr XIII:151532..148953
Primary SGDID S000004526


Description of YML061C: DNA helicase; exists in two forms; the nuclear form is involved in telomere formation and elongation; acts as a catalytic inhibitor of telomerase; the mitochondrial form is involved in repair and recombination of mitochondrial DNA[1][2][3][4]




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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically lower expression in carbon limited chemostat cultures versus carbon excess. [5] [6]





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References

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  1. Foury F and Lahaye A (1987) Cloning and sequencing of the PIF gene involved in repair and recombination of yeast mitochondrial DNA. EMBO J 6(5):1441-9 SGD PMID 3038524
  2. Ivessa AS, et al. (2000) The Saccharomyces Pif1p DNA helicase and the highly related Rrm3p have opposite effects on replication fork progression in ribosomal DNA. Cell 100(4):479-89 SGD PMID 10693764
  3. Vega LR, et al. (2007) Sensitivity of yeast strains with long g-tails to levels of telomere-bound telomerase. PLoS Genet 3(6):e105 SGD PMID 17590086
  4. Zhou J, et al. (2000) Pif1p helicase, a catalytic inhibitor of telomerase in yeast. Science 289(5480):771-4 SGD PMID 10926538
  5. Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  6. submitted by Viktor Boer on 2003-07-25

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