Difference between revisions of "YML027W"

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'''Description of YML027W:''' Homeodomain-containing transcriptional repressor, binds to Mcm1p and to early cell cycle boxes (ECBs) in the promoters of cell cycle-regulated genes expressed in M/G1 phase; expression is cell cycle-regulated; potential Cdc28p substrate<ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 {{SGDpaper|S000074306}} PMID 14574415</ref><ref name='S000072304'>Pramila T, et al. (2002) Conserved homeodomain proteins interact with MADS box protein Mcm1 to restrict ECB-dependent transcription to the M/G1 phase of the cell cycle. Genes Dev 16(23):3034-45 {{SGDpaper|S000072304}} PMID 12464633</ref><ref name='S000050068'>Kaufmann E (1993) In vitro binding to the leucine tRNA gene identifies a novel yeast homeobox gene. Chromosoma 102(3):174-9
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'''Description of YML027W:''' Homeodomain-containing transcriptional repressor, binds to Mcm1p and to early cell cycle boxes (ECBs) in the promoters of cell cycle-regulated genes expressed in M/G1 phase; expression is cell cycle-regulated; potential Cdc28p substrate<ref name='S000050068'>Kaufmann E (1993) In vitro binding to the leucine tRNA gene identifies a novel yeast homeobox gene. Chromosoma 102(3):174-9 {{SGDpaper|S000050068}} PMID 8096171</ref><ref name='S000072304'>Pramila T, et al. (2002) Conserved homeodomain proteins interact with MADS box protein Mcm1 to restrict ECB-dependent transcription to the M/G1 phase of the cell cycle. Genes Dev 16(23):3034-45 {{SGDpaper|S000072304}} PMID 12464633</ref><ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64
  {{SGDpaper|S000050068}} PMID 8096171</ref>
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  {{SGDpaper|S000074306}} PMID 14574415</ref>
 
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Revision as of 14:05, 31 March 2009

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Systematic name YML027W
Gene name YOX1
Aliases
Feature type ORF, Verified
Coordinates Chr XIII:221406..222563
Primary SGDID S000004489


Description of YML027W: Homeodomain-containing transcriptional repressor, binds to Mcm1p and to early cell cycle boxes (ECBs) in the promoters of cell cycle-regulated genes expressed in M/G1 phase; expression is cell cycle-regulated; potential Cdc28p substrate[1][2][3]




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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [3] [4]





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References

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  1. Kaufmann E (1993) In vitro binding to the leucine tRNA gene identifies a novel yeast homeobox gene. Chromosoma 102(3):174-9 SGD PMID 8096171
  2. Pramila T, et al. (2002) Conserved homeodomain proteins interact with MADS box protein Mcm1 to restrict ECB-dependent transcription to the M/G1 phase of the cell cycle. Genes Dev 16(23):3034-45 SGD PMID 12464633
  3. 3.0 3.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415 Cite error: Invalid <ref> tag; name "S000074306" defined multiple times with different content
  4. submitted by Jeff Ubersax on 2004-01-29

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