Difference between revisions of "YML010W"

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'''Description of YML010W:''' Protein that forms a complex with Spt4p and mediates both activation and inhibition of transcription elongation; Spt4p-Spt5p complex also plays a role in pre-mRNA processing<ref name='S000073348'>SGD (2003) Information without a citation in SGD  () {{SGDpaper|S000073348}} PMID </ref><ref name='S000072823'>Rondon AG, et al. (2003) Molecular evidence for a positive role of Spt4 in transcription elongation. EMBO J 22(3):612-20 {{SGDpaper|S000072823}} PMID 12554661</ref><ref name='S000072734'>Lindstrom DL, et al. (2003) Dual roles for Spt5 in pre-mRNA processing and transcription elongation revealed by identification of Spt5-associated proteins. Mol Cell Biol 23(4):1368-78 {{SGDpaper|S000072734}} PMID 12556496</ref><ref name='S000059512'>Yamaguchi Y, et al. (2001) SPT genes: key players in the regulation of transcription, chromatin structure and other cellular processes. J Biochem (Tokyo) 129(2):185-91
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'''Description of YML010W:''' Protein involved in the regulating Pol I and Pol II transcription and pre-mRNA processing; forms a complex with Spt4p<ref name='S000120445'>Schneider DA, et al. (2006) RNA polymerase II elongation factors Spt4p and Spt5p play roles in transcription elongation by RNA polymerase I and rRNA processing. Proc Natl Acad Sci U S A 103(34):12707-12 {{SGDpaper|S000120445}} PMID 16908835</ref><ref name='S000072823'>Rondon AG, et al. (2003) Molecular evidence for a positive role of Spt4 in transcription elongation. EMBO J 22(3):612-20 {{SGDpaper|S000072823}} PMID 12554661</ref><ref name='S000072734'>Lindstrom DL, et al. (2003) Dual roles for Spt5 in pre-mRNA processing and transcription elongation revealed by identification of Spt5-associated proteins. Mol Cell Biol 23(4):1368-78 {{SGDpaper|S000072734}} PMID 12556496</ref><ref name='S000059512'>Yamaguchi Y, et al. (2001) SPT genes: key players in the regulation of transcription, chromatin structure and other cellular processes. J Biochem 129(2):185-91
 
  {{SGDpaper|S000059512}} PMID 11173517</ref>
 
  {{SGDpaper|S000059512}} PMID 11173517</ref>
 
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Revision as of 07:21, 26 February 2009

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Systematic name YML010W
Gene name SPT5
Aliases
Feature type ORF, Verified
Coordinates Chr XIII:247677..250868
Primary SGDID S000004470


Description of YML010W: Protein involved in the regulating Pol I and Pol II transcription and pre-mRNA processing; forms a complex with Spt4p[1][2][3][4]




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References

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  1. Schneider DA, et al. (2006) RNA polymerase II elongation factors Spt4p and Spt5p play roles in transcription elongation by RNA polymerase I and rRNA processing. Proc Natl Acad Sci U S A 103(34):12707-12 SGD PMID 16908835
  2. Rondon AG, et al. (2003) Molecular evidence for a positive role of Spt4 in transcription elongation. EMBO J 22(3):612-20 SGD PMID 12554661
  3. Lindstrom DL, et al. (2003) Dual roles for Spt5 in pre-mRNA processing and transcription elongation revealed by identification of Spt5-associated proteins. Mol Cell Biol 23(4):1368-78 SGD PMID 12556496
  4. Yamaguchi Y, et al. (2001) SPT genes: key players in the regulation of transcription, chromatin structure and other cellular processes. J Biochem 129(2):185-91 SGD PMID 11173517

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