Difference between revisions of "YLR457C"

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'''Description of YLR457C:''' Spindle pole body (SPB) component, required for the insertion of the duplication plaque into the nuclear membrane during SPB duplication; essential for bipolar spindle formation; component of the Mps2p-Bbp1p complex<ref name='S000114231'>Araki Y, et al. (2006) The Saccharomyces cerevisiae spindle pole body (SPB) component Nbp1p is required for SPB membrane insertion and interacts with the integral membrane proteins Ndc1p and Mps2p. Mol Biol Cell 17(4):1959-70 {{SGDpaper|S000114231}} PMID 16436507</ref><ref name='S000042635'>Shimizu Y, et al. (2000) NBP1 (Nap1 binding protein 1), an essential gene for G2/M transition of Saccharomyces cerevisiae, encodes a protein of distinct sub-nuclear localization. Gene 246(1-2):395-404
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'''Description of YLR457C:''' Spindle pole body (SPB) component, required for the insertion of the duplication plaque into the nuclear membrane during SPB duplication; essential for bipolar spindle formation; component of the Mps2p-Bbp1p complex<ref name='S000042635'>Shimizu Y, et al. (2000) NBP1 (Nap1 binding protein 1), an essential gene for G2/M transition of Saccharomyces cerevisiae, encodes a protein of distinct sub-nuclear localization. Gene 246(1-2):395-404 {{SGDpaper|S000042635}} PMID 10767562</ref><ref name='S000114231'>Araki Y, et al. (2006) The Saccharomyces cerevisiae spindle pole body (SPB) component Nbp1p is required for SPB membrane insertion and interacts with the integral membrane proteins Ndc1p and Mps2p. Mol Biol Cell 17(4):1959-70
  {{SGDpaper|S000042635}} PMID 10767562</ref>
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  {{SGDpaper|S000114231}} PMID 16436507</ref>
 
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Revision as of 14:05, 31 March 2009

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Systematic name YLR457C
Gene name NBP1
Aliases
Feature type ORF, Verified
Coordinates Chr XII:1056769..1055810
Primary SGDID S000004449


Description of YLR457C: Spindle pole body (SPB) component, required for the insertion of the duplication plaque into the nuclear membrane during SPB duplication; essential for bipolar spindle formation; component of the Mps2p-Bbp1p complex[1][2]




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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [3] [4]





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References

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  1. Shimizu Y, et al. (2000) NBP1 (Nap1 binding protein 1), an essential gene for G2/M transition of Saccharomyces cerevisiae, encodes a protein of distinct sub-nuclear localization. Gene 246(1-2):395-404 SGD PMID 10767562
  2. Araki Y, et al. (2006) The Saccharomyces cerevisiae spindle pole body (SPB) component Nbp1p is required for SPB membrane insertion and interacts with the integral membrane proteins Ndc1p and Mps2p. Mol Biol Cell 17(4):1959-70 SGD PMID 16436507
  3. Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  4. submitted by Jeff Ubersax on 2004-01-29

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