Difference between revisions of "YLR442C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl? | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004434 YLR442C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''SIR3 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''SIR3 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr XII:1022248..1019312 | |nowrap| Chr XII:1022248..1019312 | ||
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004434 | ||
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<br> | <br> | ||
| − | '''Description of | + | '''Description of YLR442C:''' Silencing protein that interacts with Sir2p and Sir4p, and histone H3 and H4 tails, to establish a transcriptionally silent chromatin state; required for spreading of silenced chromatin; recruited to chromatin through interaction with Rap1p<ref name='S000068792'>Moretti P and Shore D (2001) Multiple interactions in Sir protein recruitment by Rap1p at silencers and telomeres in yeast. Mol Cell Biol 21(23):8082-94 {{SGDpaper|S000068792}} PMID 11689698</ref><ref name='S000055625'>Hecht A, et al. (1996) Spreading of transcriptional repressor SIR3 from telomeric heterochromatin. Nature 383(6595):92-6 {{SGDpaper|S000055625}} PMID 8779721</ref><ref name='S000043450'>Rine J and Herskowitz I (1987) Four genes responsible for a position effect on expression from HML and HMR in Saccharomyces cerevisiae. Genetics 116(1):9-22 |
{{SGDpaper|S000043450}} PMID 3297920</ref> | {{SGDpaper|S000043450}} PMID 3297920</ref> | ||
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J Biol Chem 278(5):3265-74</ref> | J Biol Chem 278(5):3265-74</ref> | ||
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Revision as of 08:46, 27 February 2007
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| Systematic name | YLR442C |
| Gene name | SIR3 |
| Aliases | CMT1, MAR2, STE8 |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:1022248..1019312 |
| Primary SGDID | S000004434 |
Description of YLR442C: Silencing protein that interacts with Sir2p and Sir4p, and histone H3 and H4 tails, to establish a transcriptionally silent chromatin state; required for spreading of silenced chromatin; recruited to chromatin through interaction with Rap1p[1][2][3]
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References
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- ↑ Moretti P and Shore D (2001) Multiple interactions in Sir protein recruitment by Rap1p at silencers and telomeres in yeast. Mol Cell Biol 21(23):8082-94 SGD PMID 11689698
- ↑ Hecht A, et al. (1996) Spreading of transcriptional repressor SIR3 from telomeric heterochromatin. Nature 383(6595):92-6 SGD PMID 8779721
- ↑ Rine J and Herskowitz I (1987) Four genes responsible for a position effect on expression from HML and HMR in Saccharomyces cerevisiae. Genetics 116(1):9-22 SGD PMID 3297920
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