Difference between revisions of "YLR423C"

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'''Description of YLR423C:''' Scaffold potein responsible for pre-autophagosomal structure organization; interacts with and is required for activation of Apg1p protein kinase; involved in autophagy but not in the Cvt (cytoplasm to vacuole targeting) pathway<ref name='S000120821'>Suzuki K, et al. (2007) Hierarchy of Atg proteins in pre-autophagosomal structure organization. Genes Cells 12(2):209-18 {{SGDpaper|S000120821}} PMID 17295840</ref><ref name='S000051835'>Tsukada M and Ohsumi Y (1993) Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett 333(1-2):169-74 {{SGDpaper|S000051835}} PMID 8224160</ref><ref name='S000042312'>Kamada Y, et al. (2000) Tor-mediated induction of autophagy via an Apg1 protein kinase complex. J Cell Biol 150(6):1507-13
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'''Description of YLR423C:''' Scaffold protein responsible for phagophore assembly site organization; regulatory subunit of an autophagy-specific complex that includes Atg1p and Atg13p; stimulates Atg1p kinase activity<ref name='S000120821'>Suzuki K, et al. (2007) Hierarchy of Atg proteins in pre-autophagosomal structure organization. Genes Cells 12(2):209-18 {{SGDpaper|S000120821}} PMID 17295840</ref><ref name='S000081925'>Cheong H, et al. (2005) Atg17 regulates the magnitude of the autophagic response. Mol Biol Cell 16(7):3438-53 {{SGDpaper|S000081925}} PMID 15901835</ref><ref name='S000080939'>Kabeya Y, et al. (2005) Atg17 functions in cooperation with Atg1 and Atg13 in yeast autophagy. Mol Biol Cell 16(5):2544-53 {{SGDpaper|S000080939}} PMID 15743910</ref><ref name='S000051835'>Tsukada M and Ohsumi Y (1993) Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett 333(1-2):169-74
  {{SGDpaper|S000042312}} PMID 10995454</ref>
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  {{SGDpaper|S000051835}} PMID 8224160</ref>
 
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Revision as of 07:21, 26 February 2009

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Systematic name YLR423C
Gene name ATG17
Aliases APG17
Feature type ORF, Verified
Coordinates Chr XII:973167..971914
Primary SGDID S000004415


Description of YLR423C: Scaffold protein responsible for phagophore assembly site organization; regulatory subunit of an autophagy-specific complex that includes Atg1p and Atg13p; stimulates Atg1p kinase activity[1][2][3][4]




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References

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  1. Suzuki K, et al. (2007) Hierarchy of Atg proteins in pre-autophagosomal structure organization. Genes Cells 12(2):209-18 SGD PMID 17295840
  2. Cheong H, et al. (2005) Atg17 regulates the magnitude of the autophagic response. Mol Biol Cell 16(7):3438-53 SGD PMID 15901835
  3. Kabeya Y, et al. (2005) Atg17 functions in cooperation with Atg1 and Atg13 in yeast autophagy. Mol Biol Cell 16(5):2544-53 SGD PMID 15743910
  4. Tsukada M and Ohsumi Y (1993) Isolation and characterization of autophagy-defective mutants of Saccharomyces cerevisiae. FEBS Lett 333(1-2):169-74 SGD PMID 8224160

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