YLR383W
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Systematic name | YLR383W |
Gene name | SMC6 |
Aliases | RHC18 |
Feature type | ORF, Verified |
Coordinates | Chr XII:885288..888632 |
Primary SGDID | S000004375 |
Description of YLR383W: Component of the SMC5-SMC6 complex; this complex plays a key role in the removal of X-shaped DNA structures that arise between sister chromatids during DNA replication and repair; homologous to S. pombe rad18[1][2][3]
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References
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- ↑ Bermudez-Lopez M, et al. (2010) The Smc5/6 complex is required for dissolution of DNA-mediated sister chromatid linkages. Nucleic Acids Res 38(19):6502-12 SGD PMID 20571088
- ↑ Onoda F, et al. (2004) SMC6 is required for MMS-induced interchromosomal and sister chromatid recombinations in Saccharomyces cerevisiae. DNA Repair (Amst) 3(4):429-39 SGD PMID 15010319
- ↑ Zhao X and Blobel G (2005) A SUMO ligase is part of a nuclear multiprotein complex that affects DNA repair and chromosomal organization. Proc Natl Acad Sci U S A 102(13):4777-82 SGD PMID 15738391
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