Difference between revisions of "YLR376C"
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| − | '''Description of YLR376C:''' Protein involved in a Rad51p-, Rad54p-dependent pathway for homologous recombination repair; deletion results in a mutator phenotype; deletion increases sensitivity to anticancer drugs oxaliplatin and cisplatin but not mitomycin C | + | '''Description of YLR376C:''' Protein involved in a Rad51p-, Rad54p-dependent pathway for homologous recombination repair; deletion results in a mutator phenotype; deletion increases sensitivity to anticancer drugs oxaliplatin and cisplatin but not mitomycin C<ref name='S000074096'>Huang ME, et al. (2003) A genomewide screen in Saccharomyces cerevisiae for genes that suppress the accumulation of mutations. Proc Natl Acad Sci U S A 100(20):11529-34 {{SGDpaper|S000074096}} PMID 12972632</ref><ref name='S000123652'>Mankouri HW, et al. (2007) Shu proteins promote the formation of homologous recombination intermediates that are processed by sgs1-rmi1-top3. Mol Biol Cell 18(10):4062-73 {{SGDpaper|S000123652}} PMID 17671161</ref><ref name='S000076460'>Wu HI, et al. (2004) Genome-wide identification of genes conferring resistance to the anticancer agents cisplatin, oxaliplatin, and mitomycin C. Cancer Res 64(11):3940-8 |
| − | {{SGDpaper| | + | {{SGDpaper|S000076460}} PMID 15173006</ref> |
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Revision as of 14:05, 25 February 2010
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| Systematic name | YLR376C |
| Gene name | PSY3 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:873553..872825 |
| Primary SGDID | S000004368 |
Description of YLR376C: Protein involved in a Rad51p-, Rad54p-dependent pathway for homologous recombination repair; deletion results in a mutator phenotype; deletion increases sensitivity to anticancer drugs oxaliplatin and cisplatin but not mitomycin C[1][2][3]
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References
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- ↑ Huang ME, et al. (2003) A genomewide screen in Saccharomyces cerevisiae for genes that suppress the accumulation of mutations. Proc Natl Acad Sci U S A 100(20):11529-34 SGD PMID 12972632
- ↑ Mankouri HW, et al. (2007) Shu proteins promote the formation of homologous recombination intermediates that are processed by sgs1-rmi1-top3. Mol Biol Cell 18(10):4062-73 SGD PMID 17671161
- ↑ Wu HI, et al. (2004) Genome-wide identification of genes conferring resistance to the anticancer agents cisplatin, oxaliplatin, and mitomycin C. Cancer Res 64(11):3940-8 SGD PMID 15173006
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