YLR369W
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| Systematic name | YLR369W | |
| Gene name | SSQ1 | |
| Aliases | SSC2 | |
| Feature type | ORF, Verified | |
| Coordinates | Chr XII:859551..861524 | |
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Description of YLR369W: Mitochondrial hsp70-type molecular chaperone, required for assembly of iron/sulfur clusters into proteins at a step after cluster synthesis, and for maturation of Yfh1p, which is a homolog of human frataxin implicated in Friedreich's ataxia[1][2]
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References
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- ↑ Muhlenhoff U, et al. (2003) Components involved in assembly and dislocation of iron-sulfur clusters on the scaffold protein Isu1p. EMBO J 22(18):4815-25 SGD PMID 12970193
- ↑ Knight SA, et al. (1998) Mt-Hsp70 homolog, Ssc2p, required for maturation of yeast frataxin and mitochondrial iron homeostasis. J Biol Chem 273(29):18389-93 SGD PMID 9660806
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