Difference between revisions of "YLR359W"
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| − | '''Description of YLR359W:''' Adenylosuccinate lyase, catalyzes two steps in the 'de novo' purine nucleotide biosynthetic pathway; expression is repressed by adenine and activated by Bas1p and Pho2p; mutations in human ortholog ADSL cause adenylosuccinase deficiency<ref name=' | + | '''Description of YLR359W:''' Adenylosuccinate lyase, catalyzes two steps in the 'de novo' purine nucleotide biosynthetic pathway; expression is repressed by adenine and activated by Bas1p and Pho2p; mutations in human ortholog ADSL cause adenylosuccinase deficiency<ref name='S000041612'>Denis V, et al. (1998) Role of the myb-like protein bas1p in Saccharomyces cerevisiae: a proteome analysis. Mol Microbiol 30(3):557-66 {{SGDpaper|S000041612}} PMID 9822821</ref><ref name='S000070200'>Jones EW and Fink GR (1982) Regulation of amino acid and nucleotide biosynthesis in yeast. Pp.181-299 in The Molecular Biology of the Yeast Saccharomyces: Metabolism and Gene Expression, edited by Strathern JN, Jones EW and Broach JR. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press {{SGDpaper|S000070200}} PMID </ref><ref name='S000121938'>Van den Berghe G, et al. (1997) Inborn errors of the purine nucleotide cycle: adenylosuccinase deficiency. J Inherit Metab Dis 20(2):193-202 |
| − | {{SGDpaper| | + | {{SGDpaper|S000121938}} PMID 9211192</ref> |
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Revision as of 14:05, 31 March 2009
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| Systematic name | YLR359W |
| Gene name | ADE13 |
| Aliases | BRA1, BRA8 |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:844281..845729 |
| Primary SGDID | S000004351 |
Description of YLR359W: Adenylosuccinate lyase, catalyzes two steps in the 'de novo' purine nucleotide biosynthetic pathway; expression is repressed by adenine and activated by Bas1p and Pho2p; mutations in human ortholog ADSL cause adenylosuccinase deficiency[1][2][3]
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References
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- ↑ Denis V, et al. (1998) Role of the myb-like protein bas1p in Saccharomyces cerevisiae: a proteome analysis. Mol Microbiol 30(3):557-66 SGD PMID 9822821
- ↑ Jones EW and Fink GR (1982) Regulation of amino acid and nucleotide biosynthesis in yeast. Pp.181-299 in The Molecular Biology of the Yeast Saccharomyces: Metabolism and Gene Expression, edited by Strathern JN, Jones EW and Broach JR. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press SGD PMID
- ↑ Van den Berghe G, et al. (1997) Inborn errors of the purine nucleotide cycle: adenylosuccinase deficiency. J Inherit Metab Dis 20(2):193-202 SGD PMID 9211192
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