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Systematic name YLR342W
Gene name FKS1
Aliases CND1, CWH53, ETG1, GSC1, PBR1
Feature type ORF, Verified
Coordinates Chr XII:809997..815627
Primary SGDID S000004334

Description of YLR342W: Catalytic subunit of 1,3-beta-D-glucan synthase, functionally redundant with alternate catalytic subunit Gsc2p; binds to regulatory subunit Rho1p; involved in cell wall synthesis and maintenance; localizes to sites of cell wall remodeling[1][2][3]


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  1. Douglas CM, et al. (1994) The Saccharomyces cerevisiae FKS1 (ETG1) gene encodes an integral membrane protein which is a subunit of 1,3-beta-D-glucan synthase. Proc Natl Acad Sci U S A 91(26):12907-11 SGD PMID 7528927
  2. Inoue SB, et al. (1995) Characterization and gene cloning of 1,3-beta-D-glucan synthase from Saccharomyces cerevisiae. Eur J Biochem 231(3):845-54 SGD PMID 7649185
  3. Qadota H, et al. (1996) Identification of yeast Rho1p GTPase as a regulatory subunit of 1,3-beta-glucan synthase. Science 272(5259):279-81 SGD PMID 8602515

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