Difference between revisions of "YLR288C"
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==Community Commentary== | ==Community Commentary== | ||
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==References== | ==References== | ||
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Revision as of 08:18, 30 January 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YLR288C |
| Gene name | MEC3 |
| Aliases | PIP3 |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:714906..713482 |
Description of YLR288C: DNA damage and meiotic pachytene checkpoint protein; subunit of a heterotrimeric complex (Rad17p-Mec3p-Ddc1p) that forms a sliding clamp, loaded onto partial duplex DNA by a clamp loader complex; homolog of human and S. pombe Hus1[1][2][3][4][5]
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Contents
Community Commentary
About Community Commentary. Please share your knowledge!
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References
See Help:References on how to add references
- ↑ Rouse J and Jackson SP (2002) Interfaces between the detection, signaling, and repair of DNA damage. Science 297(5581):547-51 SGD PMID 12142523
- ↑ Majka J and Burgers PM (2003) Yeast Rad17/Mec3/Ddc1: a sliding clamp for the DNA damage checkpoint. Proc Natl Acad Sci U S A 100(5):2249-54 SGD PMID 12604797
- ↑ Hong EJ and Roeder GS (2002) A role for Ddc1 in signaling meiotic double-strand breaks at the pachytene checkpoint. Genes Dev 16(3):363-76 SGD PMID 11825877
- ↑ de la Torre-Ruiz M and Lowndes NF (2000) The Saccharomyces cerevisiae DNA damage checkpoint is required for efficient repair of double strand breaks by non-homologous end joining. FEBS Lett 467(2-3):311-5 SGD PMID 10675560
- ↑ Kondo T, et al. (1999) Role of a complex containing Rad17, Mec3, and Ddc1 in the yeast DNA damage checkpoint pathway. Mol Cell Biol 19(2):1136-43 SGD PMID 9891048
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