YLR263W

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Systematic name YLR263W
Gene name RED1
Aliases
Feature type ORF, Verified
Coordinates Chr XII:670340..672823
Primary SGDID S000004253


Description of YLR263W: Protein component of the synaptonemal complex axial elements, involved in chromosome segregation during the first meiotic division; critical for coupling checkpoint signaling to SC formation; interacts with Hop1p, Mec3p and Ddc1p[1][2][3][4]




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References

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  1. Eichinger CS and Jentsch S (2010) Synaptonemal complex formation and meiotic checkpoint signaling are linked to the lateral element protein Red1. Proc Natl Acad Sci U S A 107(25):11370-5 SGD PMID 20534433
  2. Rockmill B and Roeder GS (1988) RED1: a yeast gene required for the segregation of chromosomes during the reductional division of meiosis. Proc Natl Acad Sci U S A 85(16):6057-61 SGD PMID 3413075
  3. Smith AV and Roeder GS (1997) The yeast Red1 protein localizes to the cores of meiotic chromosomes. J Cell Biol 136(5):957-67 SGD PMID 9060462
  4. Wan L, et al. (2004) Mek1 kinase activity functions downstream of RED1 in the regulation of meiotic double strand break repair in budding yeast. Mol Biol Cell 15(1):11-23 SGD PMID 14595109

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