Difference between revisions of "YLR218C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''COA4 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''COA4 ''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||'' ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases'''          ||''CMC3''
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Uncharacterized[[Category:ORF]][[Category:ORF, Uncharacterized]]
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type'''          || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]]
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
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'''Description of YLR218C:''' Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YLR218C is not essential; mutants exhibit glycogen storage defects and growth defects on a non-fermentable carbon source<ref name='S000070094'>Wilson WA, et al. (2002) Systematic identification of the genes affecting glycogen storage in the yeast Saccharomyces cerevisiae: implication of the vacuole as a determinant of glycogen level. Mol Cell Proteomics 1(3):232-42 {{SGDpaper|S000070094}} PMID 12096123</ref><ref name='S000071347'>Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 {{SGDpaper|S000071347}} PMID 12140549</ref><ref name='S000072525'>Steinmetz LM, et al. (2002) Systematic screen for human disease genes in yeast. Nat Genet 31(4):400-4 {{SGDpaper|S000072525}} PMID 12134146</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91
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'''Description of YLR218C:''' Protein that localizes to the mitochondrial intermembrane space via the Mia40p-Erv1p system; mutants exhibit glycogen storage defects and growth defects on a non-fermentable carbon source; contains twin cysteine-x9-cysteine motifs<ref name='S000070094'>Wilson WA, et al. (2002) Systematic identification of the genes affecting glycogen storage in the yeast Saccharomyces cerevisiae: implication of the vacuole as a determinant of glycogen level. Mol Cell Proteomics 1(3):232-42 {{SGDpaper|S000070094}} PMID 12096123</ref><ref name='S000071347'>Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 {{SGDpaper|S000071347}} PMID 12140549</ref><ref name='S000072525'>Steinmetz LM, et al. (2002) Systematic screen for human disease genes in yeast. Nat Genet 31(4):400-4 {{SGDpaper|S000072525}} PMID 12134146</ref><ref name='S000131381'>Longen S, et al. (2009) Systematic Analysis of the Twin Cx(9)C Protein Family. J Mol Biol
  {{SGDpaper|S000074185}} PMID 14562095</ref>
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  {{SGDpaper|S000131381}} PMID 19703468</ref>
 
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Revision as of 14:05, 14 September 2009

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Systematic name YLR218C
Gene name COA4
Aliases CMC3
Feature type ORF, Verified
Coordinates Chr XII:573920..573468
Primary SGDID S000004208


Description of YLR218C: Protein that localizes to the mitochondrial intermembrane space via the Mia40p-Erv1p system; mutants exhibit glycogen storage defects and growth defects on a non-fermentable carbon source; contains twin cysteine-x9-cysteine motifs[1][2][3][4]




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References

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  1. Wilson WA, et al. (2002) Systematic identification of the genes affecting glycogen storage in the yeast Saccharomyces cerevisiae: implication of the vacuole as a determinant of glycogen level. Mol Cell Proteomics 1(3):232-42 SGD PMID 12096123
  2. Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 SGD PMID 12140549
  3. Steinmetz LM, et al. (2002) Systematic screen for human disease genes in yeast. Nat Genet 31(4):400-4 SGD PMID 12134146
  4. Longen S, et al. (2009) Systematic Analysis of the Twin Cx(9)C Protein Family. J Mol Biol SGD PMID 19703468

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