Difference between revisions of "YLR182W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YLR182W YLR182W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004172 YLR182W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SWI6 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''SWI6 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|nowrap| Chr XII:517942..520353
 
|nowrap| Chr XII:517942..520353
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000004172
 
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'''Description of {{PAGENAME}}:''' Transcription cofactor, forms complexes with DNA-binding proteins Swi4p and Mbp1p to regulate transcription at the G1/S transition; involved in meiotic gene expression; localization regulated by phosphorylation; potential Cdc28p substrate<ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 {{SGDpaper|S000074306}} PMID 14574415</ref><ref name='S000073348'>SGD (2003) Information without a citation in SGD  () {{SGDpaper|S000073348}} PMID </ref><ref name='S000071810'>Horak CE, et al. (2002) Complex transcriptional circuitry at the G1/S transition in Saccharomyces cerevisiae. Genes Dev 16(23):3017-33 {{SGDpaper|S000071810}} PMID 12464632</ref><ref name='S000053728'>Sidorova JM, et al. (1995) Cell cycle-regulated phosphorylation of Swi6 controls its nuclear localization. Mol Biol Cell 6(12):1641-58 {{SGDpaper|S000053728}} PMID 8590795</ref><ref name='S000041257'>Leem SH, et al. (1998) Meiotic role of SWI6 in Saccharomyces cerevisiae. Nucleic Acids Res 26(13):3154-8
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'''Description of YLR182W:''' Transcription cofactor, forms complexes with DNA-binding proteins Swi4p and Mbp1p to regulate transcription at the G1/S transition; involved in meiotic gene expression; localization regulated by phosphorylation; potential Cdc28p substrate<ref name='S000074306'>Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 {{SGDpaper|S000074306}} PMID 14574415</ref><ref name='S000073348'>SGD (2003) Information without a citation in SGD  () {{SGDpaper|S000073348}} PMID </ref><ref name='S000071810'>Horak CE, et al. (2002) Complex transcriptional circuitry at the G1/S transition in Saccharomyces cerevisiae. Genes Dev 16(23):3017-33 {{SGDpaper|S000071810}} PMID 12464632</ref><ref name='S000053728'>Sidorova JM, et al. (1995) Cell cycle-regulated phosphorylation of Swi6 controls its nuclear localization. Mol Biol Cell 6(12):1641-58 {{SGDpaper|S000053728}} PMID 8590795</ref><ref name='S000041257'>Leem SH, et al. (1998) Meiotic role of SWI6 in Saccharomyces cerevisiae. Nucleic Acids Res 26(13):3154-8
 
  {{SGDpaper|S000041257}} PMID 9628912</ref>
 
  {{SGDpaper|S000041257}} PMID 9628912</ref>
 
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J Biol Chem 278(5):3265-74</ref>
 
J Biol Chem 278(5):3265-74</ref>
 
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Revision as of 08:46, 27 February 2007

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Systematic name YLR182W
Gene name SWI6
Aliases PSL8, SDS11
Feature type ORF, Verified
Coordinates Chr XII:517942..520353
Primary SGDID S000004172


Description of YLR182W: Transcription cofactor, forms complexes with DNA-binding proteins Swi4p and Mbp1p to regulate transcription at the G1/S transition; involved in meiotic gene expression; localization regulated by phosphorylation; potential Cdc28p substrate[1][2][3][4][5]




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Protein Details

Protein Modification

Modification(s): Phosphorylation

Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [1] [6]





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References

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  1. 1.0 1.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
  2. SGD (2003) Information without a citation in SGD () SGD PMID
  3. Horak CE, et al. (2002) Complex transcriptional circuitry at the G1/S transition in Saccharomyces cerevisiae. Genes Dev 16(23):3017-33 SGD PMID 12464632
  4. Sidorova JM, et al. (1995) Cell cycle-regulated phosphorylation of Swi6 controls its nuclear localization. Mol Biol Cell 6(12):1641-58 SGD PMID 8590795
  5. Leem SH, et al. (1998) Meiotic role of SWI6 in Saccharomyces cerevisiae. Nucleic Acids Res 26(13):3154-8 SGD PMID 9628912
  6. submitted by Jeff Ubersax on 2004-01-29

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