Difference between revisions of "YLR178C"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004168 YLR178C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''TFS1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''TFS1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XII: | + | |nowrap| Chr XII:513821..513162 |
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| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004168 | ||
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| − | '''Description of | + | '''Description of YLR178C:''' Protein that interacts with and inhibits carboxypeptidase Y and Ira2p; phosphatidylethanolamine-binding protein (PEBP) family member; targets to vacuolar membranes during stationary phase; acetylated by NatB N-terminal acetyltransferase<ref name='S000039310'>Bruun AW, et al. (1998) A high-affinity inhibitor of yeast carboxypeptidase Y is encoded by TFS1 and shows homology to a family of lipid binding proteins. Biochemistry 37(10):3351-7 {{SGDpaper|S000039310}} PMID 9521655</ref><ref name='S000077123'>Caesar R and Blomberg A (2004) The stress-induced Tfs1p requires NatB-mediated acetylation to inhibit carboxypeptidase Y and to regulate the protein kinase A pathway. J Biol Chem 279(37):38532-43 {{SGDpaper|S000077123}} PMID 15229224</ref><ref name='S000076056'>Chautard H, et al. (2004) Tfs1p, a member of the PEBP family, inhibits the Ira2p but not the Ira1p Ras GTPase-activating protein in Saccharomyces cerevisiae. Eukaryot Cell 3(2):459-70 {{SGDpaper|S000076056}} PMID 15075275</ref><ref name='S000130725'>Gombault A, et al. (2009) A phenotypic study of TFS1 mutants differentially altered in the inhibition of Ira2p or CPY. FEMS Yeast Res 9(6):867-74 {{SGDpaper|S000130725}} PMID 19552705</ref><ref name='S000119473'>Mima J, et al. (2006) Specific membrane binding of the carboxypeptidase Y inhibitor I(C), a phosphatidylethanolamine-binding protein family member. FEBS J 273(23):5374-83 |
| − | {{SGDpaper| | + | {{SGDpaper|S000119473}} PMID 17076703</ref> |
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| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
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Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YLR178C |
| Gene name | TFS1 |
| Aliases | DKA1 |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:513821..513162 |
| Primary SGDID | S000004168 |
Description of YLR178C: Protein that interacts with and inhibits carboxypeptidase Y and Ira2p; phosphatidylethanolamine-binding protein (PEBP) family member; targets to vacuolar membranes during stationary phase; acetylated by NatB N-terminal acetyltransferase[1][2][3][4][5]
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Contents
Community Commentary
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DNA and RNA Details
Other DNA and RNA Details
Other Topic: expression
Specifically lower expression in sulfur limited chemostat cultures versus sulfur excess. [6] [7]
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References
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- ↑ Bruun AW, et al. (1998) A high-affinity inhibitor of yeast carboxypeptidase Y is encoded by TFS1 and shows homology to a family of lipid binding proteins. Biochemistry 37(10):3351-7 SGD PMID 9521655
- ↑ Caesar R and Blomberg A (2004) The stress-induced Tfs1p requires NatB-mediated acetylation to inhibit carboxypeptidase Y and to regulate the protein kinase A pathway. J Biol Chem 279(37):38532-43 SGD PMID 15229224
- ↑ Chautard H, et al. (2004) Tfs1p, a member of the PEBP family, inhibits the Ira2p but not the Ira1p Ras GTPase-activating protein in Saccharomyces cerevisiae. Eukaryot Cell 3(2):459-70 SGD PMID 15075275
- ↑ Gombault A, et al. (2009) A phenotypic study of TFS1 mutants differentially altered in the inhibition of Ira2p or CPY. FEMS Yeast Res 9(6):867-74 SGD PMID 19552705
- ↑ Mima J, et al. (2006) Specific membrane binding of the carboxypeptidase Y inhibitor I(C), a phosphatidylethanolamine-binding protein family member. FEBS J 273(23):5374-83 SGD PMID 17076703
- ↑ Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
- ↑ submitted by Viktor Boer on 2003-07-25
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