Difference between revisions of "YLR150W"
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004140 YLR150W] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''STM1 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''STM1 '' | ||
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XII: | + | |nowrap| Chr XII:440467..441288 |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004140 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004140 | ||
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| − | '''Description of YLR150W:''' Protein required for optimal translation under nutrient stress; involved in TOR signaling | + | '''Description of YLR150W:''' Protein required for optimal translation under nutrient stress; perturbs association of Yef3p with ribosomes; involved in TOR signaling; binds G4 quadruplex and purine motif triplex nucleic acid; helps maintain telomere structure<ref name='S000071136'>Hayashi N and Murakami S (2002) STM1, a gene which encodes a guanine quadruplex binding protein, interacts with CDC13 in Saccharomyces cerevisiae. Mol Genet Genomics 267(6):806-13 {{SGDpaper|S000071136}} PMID 12207228</ref><ref name='S000051005'>Nelson LD, et al. (2000) The yeast STM1 gene encodes a purine motif triple helical DNA-binding protein. J Biol Chem 275(8):5573-81 {{SGDpaper|S000051005}} PMID 10681538</ref><ref name='S000039722'>Utsugi T, et al. (1995) A high dose of the STM1 gene suppresses the temperature sensitivity of the tom1 and htr1 mutants in Saccharomyces cerevisiae. Biochim Biophys Acta 1263(3):285-8 {{SGDpaper|S000039722}} PMID 7548221</ref><ref name='S000076387'>Van Dyke MW, et al. (2004) Stm1p, a G4 quadruplex and purine motif triplex nucleic acid-binding protein, interacts with ribosomes and subtelomeric Y' DNA in Saccharomyces cerevisiae. J Biol Chem 279(23):24323-33 {{SGDpaper|S000076387}} PMID 15044472</ref><ref name='S000114753'>Van Dyke N, et al. (2006) Stm1p, a ribosome-associated protein, is important for protein synthesis in Saccharomyces cerevisiae under nutritional stress conditions. J Mol Biol 358(4):1023-31 {{SGDpaper|S000114753}} PMID 16580682</ref><ref name='S000131187'>Van Dyke N, et al. (2009) Stm1p alters the ribosome association of eukaryotic elongation factor 3 and affects translation elongation. Nucleic Acids Res 37(18):6116-25 |
| − | {{SGDpaper| | + | {{SGDpaper|S000131187}} PMID 19666721</ref> |
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Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YLR150W |
| Gene name | STM1 |
| Aliases | MPT4 |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:440467..441288 |
| Primary SGDID | S000004140 |
Description of YLR150W: Protein required for optimal translation under nutrient stress; perturbs association of Yef3p with ribosomes; involved in TOR signaling; binds G4 quadruplex and purine motif triplex nucleic acid; helps maintain telomere structure[1][2][3][4][5][6]
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References
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- ↑ Hayashi N and Murakami S (2002) STM1, a gene which encodes a guanine quadruplex binding protein, interacts with CDC13 in Saccharomyces cerevisiae. Mol Genet Genomics 267(6):806-13 SGD PMID 12207228
- ↑ Nelson LD, et al. (2000) The yeast STM1 gene encodes a purine motif triple helical DNA-binding protein. J Biol Chem 275(8):5573-81 SGD PMID 10681538
- ↑ Utsugi T, et al. (1995) A high dose of the STM1 gene suppresses the temperature sensitivity of the tom1 and htr1 mutants in Saccharomyces cerevisiae. Biochim Biophys Acta 1263(3):285-8 SGD PMID 7548221
- ↑ Van Dyke MW, et al. (2004) Stm1p, a G4 quadruplex and purine motif triplex nucleic acid-binding protein, interacts with ribosomes and subtelomeric Y' DNA in Saccharomyces cerevisiae. J Biol Chem 279(23):24323-33 SGD PMID 15044472
- ↑ Van Dyke N, et al. (2006) Stm1p, a ribosome-associated protein, is important for protein synthesis in Saccharomyces cerevisiae under nutritional stress conditions. J Mol Biol 358(4):1023-31 SGD PMID 16580682
- ↑ Van Dyke N, et al. (2009) Stm1p alters the ribosome association of eukaryotic elongation factor 3 and affects translation elongation. Nucleic Acids Res 37(18):6116-25 SGD PMID 19666721
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