Difference between revisions of "YLR131C"
SGDwikiBot (talk | contribs) (Automated import of articles) |
SGDwikiBot (talk | contribs) (Automated import of articles) |
||
| (9 intermediate revisions by the same user not shown) | |||
| Line 4: | Line 4: | ||
{|{{Prettytable}} align = 'right' width = '200px' | {|{{Prettytable}} align = 'right' width = '200px' | ||
|- | |- | ||
| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000004121 YLR131C] |
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ACE2 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''ACE2 '' | ||
| Line 13: | Line 13: | ||
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr XII: | + | |nowrap| Chr XII:406822..404510 |
| + | |- | ||
| + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000004121 | ||
|} | |} | ||
<br> | <br> | ||
| − | '''Description of | + | '''Description of YLR131C:''' Transcription factor required for septum destruction after cytokinesis; phosphorylation by Cbk1p blocks nuclear exit of Ace2p during the M-to-G1 transition, causing its specific localization to daughter cell nuclei, and also increases Ace2p activity; phosphorylation by Cdc28p and Pho85p prevents nuclear import during cell cycle phases other than cytokinesis; part of the RAM network that regulates cellular polarity and morphogenesis<ref name='S000060221'>Bidlingmaier S, et al. (2001) The Cbk1p pathway is important for polarized cell growth and cell separation in Saccharomyces cerevisiae. Mol Cell Biol 21(7):2449-62 {{SGDpaper|S000060221}} PMID 11259593</ref><ref name='S000054707'>Dohrmann PR, et al. (1992) Parallel pathways of gene regulation: homologous regulators SWI5 and ACE2 differentially control transcription of HO and chitinase. Genes Dev 6(1):93-104 {{SGDpaper|S000054707}} PMID 1730413</ref><ref name='S000054168'>Dohrmann PR, et al. (1996) Role of negative regulation in promoter specificity of the homologous transcriptional activators Ace2p and Swi5p. Mol Cell Biol 16(4):1746-58 {{SGDpaper|S000054168}} PMID 8657150</ref><ref name='S000073921'>Laabs TL, et al. (2003) ACE2 is required for daughter cell-specific G1 delay in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 100(18):10275-80 {{SGDpaper|S000073921}} PMID 12937340</ref><ref name='S000134510'>Mazanka E and Weiss EL (2010) Sequential Counteracting Kinases Restrict an Asymmetric Gene Expression Program to early G1. Mol Biol Cell 21(16):2809-20 {{SGDpaper|S000134510}} PMID 20573982</ref><ref name='S000127452'>Mazanka E, et al. (2008) The NDR/LATS family kinase Cbk1 directly controls transcriptional asymmetry. PLoS Biol 6(8):e203 {{SGDpaper|S000127452}} PMID 18715118</ref><ref name='S000074101'>Nelson B, et al. (2003) RAM: a conserved signaling network that regulates Ace2p transcriptional activity and polarized morphogenesis. Mol Biol Cell 14(9):3782-803 {{SGDpaper|S000074101}} PMID 12972564</ref><ref name='S000048452'>O'Conallain C, et al. (1999) Regulated nuclear localisation of the yeast transcription factor Ace2p controls expression of chitinase (CTS1) in Saccharomyces cerevisiae. Mol Gen Genet 262(2):275-82 {{SGDpaper|S000048452}} PMID 10517323</ref><ref name='S000125606'>Sbia M, et al. (2008) Regulation of the yeast Ace2 transcription factor during the cell cycle. J Biol Chem 283(17):11135-45 |
| − | {{SGDpaper| | + | {{SGDpaper|S000125606}} PMID 18292088</ref> |
<br> | <br> | ||
<br> | <br> | ||
| Line 36: | Line 38: | ||
{{ShortCenteredHR}} | {{ShortCenteredHR}} | ||
| + | |||
| + | |||
| + | |||
| + | <!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation --> | ||
| + | <!-- | ||
| + | Specifically higher expression in carbon limited chemostat cultures versus carbon excess. | ||
| + | <ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. | ||
| + | J Biol Chem 278(5):3265-74</ref> | ||
| + | --> | ||
| + | |||
| + | |||
<protect> | <protect> | ||
Latest revision as of 07:45, 23 January 2012
Share your knowledge...Edit this entry! <protect>
| Systematic name | YLR131C |
| Gene name | ACE2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:406822..404510 |
| Primary SGDID | S000004121 |
Description of YLR131C: Transcription factor required for septum destruction after cytokinesis; phosphorylation by Cbk1p blocks nuclear exit of Ace2p during the M-to-G1 transition, causing its specific localization to daughter cell nuclei, and also increases Ace2p activity; phosphorylation by Cdc28p and Pho85p prevents nuclear import during cell cycle phases other than cytokinesis; part of the RAM network that regulates cellular polarity and morphogenesis[1][2][3][4][5][6][7][8][9]
</protect>
Community Commentary
About Community Commentary. Please share your knowledge!
Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [10] [11]
<protect>
References
See Help:References on how to add references
- ↑ Bidlingmaier S, et al. (2001) The Cbk1p pathway is important for polarized cell growth and cell separation in Saccharomyces cerevisiae. Mol Cell Biol 21(7):2449-62 SGD PMID 11259593
- ↑ Dohrmann PR, et al. (1992) Parallel pathways of gene regulation: homologous regulators SWI5 and ACE2 differentially control transcription of HO and chitinase. Genes Dev 6(1):93-104 SGD PMID 1730413
- ↑ Dohrmann PR, et al. (1996) Role of negative regulation in promoter specificity of the homologous transcriptional activators Ace2p and Swi5p. Mol Cell Biol 16(4):1746-58 SGD PMID 8657150
- ↑ Laabs TL, et al. (2003) ACE2 is required for daughter cell-specific G1 delay in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 100(18):10275-80 SGD PMID 12937340
- ↑ Mazanka E and Weiss EL (2010) Sequential Counteracting Kinases Restrict an Asymmetric Gene Expression Program to early G1. Mol Biol Cell 21(16):2809-20 SGD PMID 20573982
- ↑ Mazanka E, et al. (2008) The NDR/LATS family kinase Cbk1 directly controls transcriptional asymmetry. PLoS Biol 6(8):e203 SGD PMID 18715118
- ↑ Nelson B, et al. (2003) RAM: a conserved signaling network that regulates Ace2p transcriptional activity and polarized morphogenesis. Mol Biol Cell 14(9):3782-803 SGD PMID 12972564
- ↑ O'Conallain C, et al. (1999) Regulated nuclear localisation of the yeast transcription factor Ace2p controls expression of chitinase (CTS1) in Saccharomyces cerevisiae. Mol Gen Genet 262(2):275-82 SGD PMID 10517323
- ↑ Sbia M, et al. (2008) Regulation of the yeast Ace2 transcription factor during the cell cycle. J Biol Chem 283(17):11135-45 SGD PMID 18292088
- ↑ Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ submitted by Jeff Ubersax on 2004-01-29
See Help:Categories on how to add the wiki page for this gene to a Category </protect>
