Difference between revisions of "YLR118C"

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'''Description of YLR118C:''' Acyl-protein thioesterase responsible for depalmitoylation of Gpa1p; the mutant has no gross defects in signaling through the mating pathway; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus<ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000070379'>Duncan JA and Gilman AG (2002) Characterization of Saccharomyces cerevisiae acyl-protein thioesterase 1, the enzyme responsible for G protein alpha subunit deacylation in vivo. J Biol Chem 277(35):31740-52
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'''Description of YLR118C:''' Acyl-protein thioesterase responsible for depalmitoylation of Gpa1p; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and nucleus and is induced in response to the DNA-damaging agent MMS<ref name='S000121916'>Lee MW, et al. (2007) Global protein expression profiling of budding yeast in response to DNA damage. Yeast 24(3):145-54 {{SGDpaper|S000121916}} PMID 17351896</ref><ref name='S000074185'>Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 {{SGDpaper|S000074185}} PMID 14562095</ref><ref name='S000070379'>Duncan JA and Gilman AG (2002) Characterization of Saccharomyces cerevisiae acyl-protein thioesterase 1, the enzyme responsible for G protein alpha subunit deacylation in vivo. J Biol Chem 277(35):31740-52
 
  {{SGDpaper|S000070379}} PMID 12080046</ref>
 
  {{SGDpaper|S000070379}} PMID 12080046</ref>
 
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Revision as of 15:05, 21 March 2007

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Systematic name YLR118C
Gene name
Aliases APT1
Feature type ORF, Verified
Coordinates Chr XII:385409..384726
Primary SGDID S000004108


Description of YLR118C: Acyl-protein thioesterase responsible for depalmitoylation of Gpa1p; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and nucleus and is induced in response to the DNA-damaging agent MMS[1][2][3]




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References

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  1. Lee MW, et al. (2007) Global protein expression profiling of budding yeast in response to DNA damage. Yeast 24(3):145-54 SGD PMID 17351896
  2. Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
  3. Duncan JA and Gilman AG (2002) Characterization of Saccharomyces cerevisiae acyl-protein thioesterase 1, the enzyme responsible for G protein alpha subunit deacylation in vivo. J Biol Chem 277(35):31740-52 SGD PMID 12080046

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