YLR059C

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Systematic name YLR059C
Gene name REX2
Aliases YNT20
Feature type ORF, Verified
Coordinates Chr XII:260547..259738
Primary SGDID S000004049


Description of YLR059C: 3'-5' RNA exonuclease; involved in 3'-end processing of U4 and U5 snRNAs, 5S and 5.8S rRNAs, and RNase P and RNase MRP RNA; localized to mitochondria and null suppresses escape of mtDNA to nucleus in yme1 yme2 mutants; RNase D exonuclease[1][2]




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References

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  1. Hanekamp T and Thorsness PE (1999) YNT20, a bypass suppressor of yme1 yme2, encodes a putative 3'-5' exonuclease localized in mitochondria of Saccharomyces cerevisiae. Curr Genet 34(6):438-48 SGD PMID 9933355
  2. van Hoof A, et al. (2000) Three conserved members of the RNase D family have unique and overlapping functions in the processing of 5S, 5.8S, U4, U5, RNase MRP and RNase P RNAs in yeast. EMBO J 19(6):1357-65 SGD PMID 10716935

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