Difference between revisions of "YLL043W"
SGDwikiBot (talk | contribs) (Automated import of articles) |
(→Community Commentary) |
||
| Line 38: | Line 38: | ||
{{ShortCenteredHR}} | {{ShortCenteredHR}} | ||
| − | + | The main role of Fps1 is export of glycerol for osmoregulation. Fps1 transport function is gated to ensure glycerol accummulation and glycerol release depending on osmotic conditions. | |
<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation --> | <!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation --> | ||
| Line 50: | Line 50: | ||
<protect> | <protect> | ||
| + | |||
==References== | ==References== | ||
<!-- REFERENCES ARE AUTOMATICALLY GENERATED. PLEASE DON'T EDIT THIS SECTION--> | <!-- REFERENCES ARE AUTOMATICALLY GENERATED. PLEASE DON'T EDIT THIS SECTION--> | ||
{{RefHelp}} | {{RefHelp}} | ||
</protect> | </protect> | ||
Revision as of 08:08, 4 May 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YLL043W |
| Gene name | FPS1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:49937..51946 |
| Primary SGDID | S000003966 |
Description of YLL043W: Plasma membrane glycerol channel, member of the major intrinsic protein (MIP) family of channel proteins; involved in efflux of glycerol and in uptake of the trivalent metalloids arsenite and antimonite[1][2][3]
</protect>
Community Commentary
About Community Commentary. Please share your knowledge!
Protein Details
Protein Function/Process
Disruption of the FPS1 gene for the aquaglyceroporin Fps1p reduced uptake of 73As(III) into cells, conferring resistance to arsenite. The arsenate-resistant phenotype could be functionally complemented by expression of AQP9, a mammalian homologue [4] [5]
The main role of Fps1 is export of glycerol for osmoregulation. Fps1 transport function is gated to ensure glycerol accummulation and glycerol release depending on osmotic conditions.
<protect>
References
See Help:References on how to add references
- ↑ Wysocki R, et al. (2001) The glycerol channel Fps1p mediates the uptake of arsenite and antimonite in Saccharomyces cerevisiae. Mol Microbiol 40(6):1391-401 SGD PMID 11442837
- ↑ Luyten K, et al. (1995) Fps1, a yeast member of the MIP family of channel proteins, is a facilitator for glycerol uptake and efflux and is inactive under osmotic stress. EMBO J 14(7):1360-71 SGD PMID 7729414
- ↑ Tamas MJ, et al. (1999) Fps1p controls the accumulation and release of the compatible solute glycerol in yeast osmoregulation. Mol Microbiol 31(4):1087-104 SGD PMID 10096077
- ↑ Liu Z, et al. (2002) Arsenite transport by mammalian aquaglyceroporins AQP7 and AQP9. Proc Natl Acad Sci U S A 99(9):6053-8 SGD PMID 11972053
- ↑ submitted by Barry Rosen on 2003-07-31
See Help:Categories on how to add the wiki page for this gene to a Category </protect>
