Difference between revisions of "YKR097W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001805 YKR097W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001805 YKR097W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PCK1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''PCK1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XI:630790..632439
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|nowrap| Chr XI:631152..632801
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001805
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001805
 
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'''Description of YKR097W:''' Phosphoenolpyruvate carboxykinase, key enzyme in gluconeogenesis, catalyzes early reaction in carbohydrate biosynthesis, glucose represses transcription and accelerates mRNA degradation, regulated by Mcm1p and Cat8p, located in the cytosol<ref name='S000064319'>Llanos L, et al. (2001) Mutation Arg336 to Lys in Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase originates an enzyme with increased oxaloacetate decarboxylase activity. FEBS Lett 493(1):1-5 {{SGDpaper|S000064319}} PMID 11277994</ref><ref name='S000064314'>Haarasilta S and Oura E (1975) On the activity and regulation of anaplerotic and gluconeogenetic enzymes during the growth process of baker's yeast. The biphasic growth. Eur J Biochem 52(1):1-7 {{SGDpaper|S000064314}} PMID 170081</ref><ref name='S000056699'>Haarasilta S and Taskinen L (1977) Location of three key enzymes of gluconeogenesis in baker's yeast. Arch Microbiol 113(1-2):159-61 {{SGDpaper|S000056699}} PMID 196563</ref><ref name='S000053348'>Valdes-Hevia MD, et al. (1989) Isolation and characterization of the gene encoding phosphoenolpyruvate carboxykinase from Saccharomyces cerevisiae. FEBS Lett 258(2):313-6 {{SGDpaper|S000053348}} PMID 2689220</ref><ref name='S000053054'>Proft M, et al. (1995) Identification and characterization of regulatory elements in the phosphoenolpyruvate carboxykinase gene PCK1 of Saccharomyces cerevisiae. Mol Gen Genet 246(3):367-73 {{SGDpaper|S000053054}} PMID 7854322</ref><ref name='S000050515'>Kuo MH and Grayhack E (1994) A library of yeast genomic MCM1 binding sites contains genes involved in cell cycle control, cell wall and membrane structure, and metabolism. Mol Cell Biol 14(1):348-59 {{SGDpaper|S000050515}} PMID 8264602</ref><ref name='S000047103'>Yin Z, et al. (2000) Differential post-transcriptional regulation of yeast mRNAs in response to high and low glucose concentrations. Mol Microbiol 35(3):553-65 {{SGDpaper|S000047103}} PMID 10672178</ref><ref name='S000043068'>Haurie V, et al. (2001) The transcriptional activator Cat8p provides a major contribution to the reprogramming of carbon metabolism during the diauxic shift in Saccharomyces cerevisiae. J Biol Chem 276(1):76-85
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'''Description of YKR097W:''' Phosphoenolpyruvate carboxykinase, key enzyme in gluconeogenesis, catalyzes early reaction in carbohydrate biosynthesis, glucose represses transcription and accelerates mRNA degradation, regulated by Mcm1p and Cat8p, located in the cytosol<ref name='S000064314'>Haarasilta S and Oura E (1975) On the activity and regulation of anaplerotic and gluconeogenetic enzymes during the growth process of baker's yeast. The biphasic growth. Eur J Biochem 52(1):1-7 {{SGDpaper|S000064314}} PMID 170081</ref><ref name='S000056699'>Haarasilta S and Taskinen L (1977) Location of three key enzymes of gluconeogenesis in baker's yeast. Arch Microbiol 113(1-2):159-61 {{SGDpaper|S000056699}} PMID 196563</ref><ref name='S000043068'>Haurie V, et al. (2001) The transcriptional activator Cat8p provides a major contribution to the reprogramming of carbon metabolism during the diauxic shift in Saccharomyces cerevisiae. J Biol Chem 276(1):76-85 {{SGDpaper|S000043068}} PMID 11024040</ref><ref name='S000050515'>Kuo MH and Grayhack E (1994) A library of yeast genomic MCM1 binding sites contains genes involved in cell cycle control, cell wall and membrane structure, and metabolism. Mol Cell Biol 14(1):348-59 {{SGDpaper|S000050515}} PMID 8264602</ref><ref name='S000064319'>Llanos L, et al. (2001) Mutation Arg336 to Lys in Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase originates an enzyme with increased oxaloacetate decarboxylase activity. FEBS Lett 493(1):1-5 {{SGDpaper|S000064319}} PMID 11277994</ref><ref name='S000053054'>Proft M, et al. (1995) Identification and characterization of regulatory elements in the phosphoenolpyruvate carboxykinase gene PCK1 of Saccharomyces cerevisiae. Mol Gen Genet 246(3):367-73 {{SGDpaper|S000053054}} PMID 7854322</ref><ref name='S000053348'>Valdes-Hevia MD, et al. (1989) Isolation and characterization of the gene encoding phosphoenolpyruvate carboxykinase from Saccharomyces cerevisiae. FEBS Lett 258(2):313-6 {{SGDpaper|S000053348}} PMID 2689220</ref><ref name='S000047103'>Yin Z, et al. (2000) Differential post-transcriptional regulation of yeast mRNAs in response to high and low glucose concentrations. Mol Microbiol 35(3):553-65
{{SGDpaper|S000043068}} PMID 11024040</ref>
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{{SGDpaper|S000047103}} PMID 10672178</ref>
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YKR097W
Gene name PCK1
Aliases JPM2, PPC1
Feature type ORF, Verified
Coordinates Chr XI:631152..632801
Primary SGDID S000001805


Description of YKR097W: Phosphoenolpyruvate carboxykinase, key enzyme in gluconeogenesis, catalyzes early reaction in carbohydrate biosynthesis, glucose represses transcription and accelerates mRNA degradation, regulated by Mcm1p and Cat8p, located in the cytosol[1][2][3][4][5][6][7][8]




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References

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  1. Haarasilta S and Oura E (1975) On the activity and regulation of anaplerotic and gluconeogenetic enzymes during the growth process of baker's yeast. The biphasic growth. Eur J Biochem 52(1):1-7 SGD PMID 170081
  2. Haarasilta S and Taskinen L (1977) Location of three key enzymes of gluconeogenesis in baker's yeast. Arch Microbiol 113(1-2):159-61 SGD PMID 196563
  3. Haurie V, et al. (2001) The transcriptional activator Cat8p provides a major contribution to the reprogramming of carbon metabolism during the diauxic shift in Saccharomyces cerevisiae. J Biol Chem 276(1):76-85 SGD PMID 11024040
  4. Kuo MH and Grayhack E (1994) A library of yeast genomic MCM1 binding sites contains genes involved in cell cycle control, cell wall and membrane structure, and metabolism. Mol Cell Biol 14(1):348-59 SGD PMID 8264602
  5. Llanos L, et al. (2001) Mutation Arg336 to Lys in Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase originates an enzyme with increased oxaloacetate decarboxylase activity. FEBS Lett 493(1):1-5 SGD PMID 11277994
  6. Proft M, et al. (1995) Identification and characterization of regulatory elements in the phosphoenolpyruvate carboxykinase gene PCK1 of Saccharomyces cerevisiae. Mol Gen Genet 246(3):367-73 SGD PMID 7854322
  7. Valdes-Hevia MD, et al. (1989) Isolation and characterization of the gene encoding phosphoenolpyruvate carboxykinase from Saccharomyces cerevisiae. FEBS Lett 258(2):313-6 SGD PMID 2689220
  8. Yin Z, et al. (2000) Differential post-transcriptional regulation of yeast mRNAs in response to high and low glucose concentrations. Mol Microbiol 35(3):553-65 SGD PMID 10672178

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