Difference between revisions of "YKR097W"
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| − | '''Description of YKR097W:''' Phosphoenolpyruvate carboxykinase, key enzyme in gluconeogenesis, catalyzes early reaction in carbohydrate biosynthesis, glucose represses transcription and accelerates mRNA degradation, regulated by Mcm1p and Cat8p, located in the cytosol<ref name=' | + | '''Description of YKR097W:''' Phosphoenolpyruvate carboxykinase, key enzyme in gluconeogenesis, catalyzes early reaction in carbohydrate biosynthesis, glucose represses transcription and accelerates mRNA degradation, regulated by Mcm1p and Cat8p, located in the cytosol<ref name='S000043068'>Haurie V, et al. (2001) The transcriptional activator Cat8p provides a major contribution to the reprogramming of carbon metabolism during the diauxic shift in Saccharomyces cerevisiae. J Biol Chem 276(1):76-85 {{SGDpaper|S000043068}} PMID 11024040</ref><ref name='S000047103'>Yin Z, et al. (2000) Differential post-transcriptional regulation of yeast mRNAs in response to high and low glucose concentrations. Mol Microbiol 35(3):553-65 {{SGDpaper|S000047103}} PMID 10672178</ref><ref name='S000050515'>Kuo MH and Grayhack E (1994) A library of yeast genomic MCM1 binding sites contains genes involved in cell cycle control, cell wall and membrane structure, and metabolism. Mol Cell Biol 14(1):348-59 {{SGDpaper|S000050515}} PMID 8264602</ref><ref name='S000053054'>Proft M, et al. (1995) Identification and characterization of regulatory elements in the phosphoenolpyruvate carboxykinase gene PCK1 of Saccharomyces cerevisiae. Mol Gen Genet 246(3):367-73 {{SGDpaper|S000053054}} PMID 7854322</ref><ref name='S000053348'>Valdes-Hevia MD, et al. (1989) Isolation and characterization of the gene encoding phosphoenolpyruvate carboxykinase from Saccharomyces cerevisiae. FEBS Lett 258(2):313-6 {{SGDpaper|S000053348}} PMID 2689220</ref><ref name='S000056699'>Haarasilta S and Taskinen L (1977) Location of three key enzymes of gluconeogenesis in baker's yeast. Arch Microbiol 113(1-2):159-61 {{SGDpaper|S000056699}} PMID 196563</ref><ref name='S000064314'>Haarasilta S and Oura E (1975) On the activity and regulation of anaplerotic and gluconeogenetic enzymes during the growth process of baker's yeast. The biphasic growth. Eur J Biochem 52(1):1-7 {{SGDpaper|S000064314}} PMID 170081</ref><ref name='S000064319'>Llanos L, et al. (2001) Mutation Arg336 to Lys in Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase originates an enzyme with increased oxaloacetate decarboxylase activity. FEBS Lett 493(1):1-5 |
| − | {{SGDpaper| | + | {{SGDpaper|S000064319}} PMID 11277994</ref> |
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Revision as of 14:05, 31 March 2009
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| Systematic name | YKR097W |
| Gene name | PCK1 |
| Aliases | JPM2, PPC1 |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:630790..632439 |
| Primary SGDID | S000001805 |
Description of YKR097W: Phosphoenolpyruvate carboxykinase, key enzyme in gluconeogenesis, catalyzes early reaction in carbohydrate biosynthesis, glucose represses transcription and accelerates mRNA degradation, regulated by Mcm1p and Cat8p, located in the cytosol[1][2][3][4][5][6][7][8]
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References
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- ↑ Haurie V, et al. (2001) The transcriptional activator Cat8p provides a major contribution to the reprogramming of carbon metabolism during the diauxic shift in Saccharomyces cerevisiae. J Biol Chem 276(1):76-85 SGD PMID 11024040
- ↑ Yin Z, et al. (2000) Differential post-transcriptional regulation of yeast mRNAs in response to high and low glucose concentrations. Mol Microbiol 35(3):553-65 SGD PMID 10672178
- ↑ Kuo MH and Grayhack E (1994) A library of yeast genomic MCM1 binding sites contains genes involved in cell cycle control, cell wall and membrane structure, and metabolism. Mol Cell Biol 14(1):348-59 SGD PMID 8264602
- ↑ Proft M, et al. (1995) Identification and characterization of regulatory elements in the phosphoenolpyruvate carboxykinase gene PCK1 of Saccharomyces cerevisiae. Mol Gen Genet 246(3):367-73 SGD PMID 7854322
- ↑ Valdes-Hevia MD, et al. (1989) Isolation and characterization of the gene encoding phosphoenolpyruvate carboxykinase from Saccharomyces cerevisiae. FEBS Lett 258(2):313-6 SGD PMID 2689220
- ↑ Haarasilta S and Taskinen L (1977) Location of three key enzymes of gluconeogenesis in baker's yeast. Arch Microbiol 113(1-2):159-61 SGD PMID 196563
- ↑ Haarasilta S and Oura E (1975) On the activity and regulation of anaplerotic and gluconeogenetic enzymes during the growth process of baker's yeast. The biphasic growth. Eur J Biochem 52(1):1-7 SGD PMID 170081
- ↑ Llanos L, et al. (2001) Mutation Arg336 to Lys in Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase originates an enzyme with increased oxaloacetate decarboxylase activity. FEBS Lett 493(1):1-5 SGD PMID 11277994
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