Difference between revisions of "YKR086W"
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| − | '''Description of YKR086W:''' | + | '''Description of YKR086W:''' DEAH-box RNA helicase involved in second catalytic step of splicing; exhibits ATP-dependent RNA unwinding activity; mediates the release of Yju2p and Cwc25p in the second step; in the absence of ATP, stabilizes the binding of Cwc25p to the spliceosome in the first catalytic step<ref name='S000144152'>Tseng CK, et al. (2011) DEAH-box ATPase Prp16 has dual roles in remodeling of the spliceosome in catalytic steps. RNA 17(1):145-54 {{SGDpaper|S000144152}} PMID 21098140</ref><ref name='S000074855'>Umen JG and Guthrie C (1995) The second catalytic step of pre-mRNA splicing. RNA 1(9):869-85 {{SGDpaper|S000074855}} PMID 8548652</ref><ref name='S000048051'>Wang Y, et al. (1998) The DEAH-box splicing factor Prp16 unwinds RNA duplexes in vitro. Curr Biol 8(8):441-51 |
{{SGDpaper|S000048051}} PMID 9550699</ref> | {{SGDpaper|S000048051}} PMID 9550699</ref> | ||
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Revision as of 14:05, 11 May 2011
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| Systematic name | YKR086W |
| Gene name | PRP16 |
| Aliases | PRP23, RNA16 |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:599857..603072 |
| Primary SGDID | S000001794 |
Description of YKR086W: DEAH-box RNA helicase involved in second catalytic step of splicing; exhibits ATP-dependent RNA unwinding activity; mediates the release of Yju2p and Cwc25p in the second step; in the absence of ATP, stabilizes the binding of Cwc25p to the spliceosome in the first catalytic step[1][2][3]
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References
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- ↑ Tseng CK, et al. (2011) DEAH-box ATPase Prp16 has dual roles in remodeling of the spliceosome in catalytic steps. RNA 17(1):145-54 SGD PMID 21098140
- ↑ Umen JG and Guthrie C (1995) The second catalytic step of pre-mRNA splicing. RNA 1(9):869-85 SGD PMID 8548652
- ↑ Wang Y, et al. (1998) The DEAH-box splicing factor Prp16 unwinds RNA duplexes in vitro. Curr Biol 8(8):441-51 SGD PMID 9550699
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