Difference between revisions of "YKR065C"

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'''Description of YKR065C:''' Presequence translocase-associated motor subunit, required for stable complex formation between cochaperones Pam16p and Pam18p, promotes association of Pam16p-Pam18p with the presequence translocase<ref name='S000114729'>van der Laan M, et al. (2005) Pam17 is required for architecture and translocation activity of the mitochondrial protein import motor. Mol Cell Biol 25(17):7449-58
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'''Description of YKR065C:''' Constituent of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); proposed alternatively to be a component of the import motor (PAM complex) or to interact with and modulate the core TIM23 complex<ref name='S000114729'>van der Laan M, et al. (2005) Pam17 is required for architecture and translocation activity of the mitochondrial protein import motor. Mol Cell Biol 25(17):7449-58 {{SGDpaper|S000114729}} PMID 16107694</ref><ref name='S000129493'>Popov-Celeketic D, et al. (2008) Active remodelling of the TIM23 complex during translocation of preproteins into mitochondria. EMBO J 27(10):1469-80
  {{SGDpaper|S000114729}} PMID 16107694</ref>
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  {{SGDpaper|S000129493}} PMID 18418384</ref>
 
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Revision as of 14:05, 4 August 2009

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Systematic name YKR065C
Gene name PAM17
Aliases FMP18
Feature type ORF, Verified
Coordinates Chr XI:565534..564941
Primary SGDID S000001773


Description of YKR065C: Constituent of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); proposed alternatively to be a component of the import motor (PAM complex) or to interact with and modulate the core TIM23 complex[1][2]




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Protein Details

Protein Localization

Protein identified in a purified mitochondrial extract. [3] [4]





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References

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  1. van der Laan M, et al. (2005) Pam17 is required for architecture and translocation activity of the mitochondrial protein import motor. Mol Cell Biol 25(17):7449-58 SGD PMID 16107694
  2. Popov-Celeketic D, et al. (2008) Active remodelling of the TIM23 complex during translocation of preproteins into mitochondria. EMBO J 27(10):1469-80 SGD PMID 18418384
  3. Ohlmeier S, et al. (2004) The yeast mitochondrial proteome, a study of fermentative and respiratory growth. J Biol Chem 279(6):3956-79 SGD PMID 14597615
  4. submitted by Steffen Ohlmeier on 2004-04-08

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