Difference between revisions of "YKR042W"

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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Revision as of 13:02, 21 February 2007

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Systematic name YKR042W
Gene name UTH1
Aliases
Feature type ORF, Verified
Coordinates Chr XI:519169..520266


Description of YKR042W: Mitochondrial outer membrane and cell wall localized SUN family member required for mitochondrial autophagy; involved in the oxidative stress response, life span during starvation, mitochondrial biogenesis, and cell death[1][2][3][4][5][6]




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References

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  1. Camougrand N, et al. (2003) The product of the UTH1 gene, required for Bax-induced cell death in yeast, is involved in the response to rapamycin. Mol Microbiol 47(2):495-506 SGD PMID 12519199
  2. Kissova I, et al. (2004) Uth1p is involved in the autophagic degradation of mitochondria. J Biol Chem 279(37):39068-74 SGD PMID 15247238
  3. Velours G, et al. (2002) Dual cell wall/mitochondria localization of the 'SUN' family proteins. FEMS Microbiol Lett 207(2):165-72 SGD PMID 11958935
  4. Camougrand NM, et al. (2000) The "SUN" family: UTH1, an ageing gene, is also involved in the regulation of mitochondria biogenesis in Saccharomyces cerevisiae. Arch Biochem Biophys 375(1):154-60 SGD PMID 10683261
  5. Bandara PD, et al. (1998) Involvement of the Saccharomyces cerevisiae UTH1 gene in the oxidative-stress response. Curr Genet 34(4):259-68 SGD PMID 9799359
  6. Kennedy BK, et al. (1995) Mutation in the silencing gene SIR4 can delay aging in S. cerevisiae. Cell 80(3):485-96 SGD PMID 7859289

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