Difference between revisions of "YKR019C"

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'''Description of YKR019C:''' EH domain-containing protein involved in regulating phosphatidylinositol 4,5-bisphosphate levels and autophagy; Irs4p and Tax4p bind and activate the PtdIns phosphatase Inp51p; Irs4p and Tax4p are involved in localizing Atg17p to the PAS<ref name='S000040062'>Paoluzi S, et al. (1998) Recognition specificity of individual EH domains of mammals and yeast. EMBO J 17(22):6541-50 {{SGDpaper|S000040062}} PMID 9822599</ref><ref name='S000054483'>Smith JS, et al. (1999) A genetic screen for ribosomal DNA silencing defects identifies multiple DNA replication and chromatin-modulating factors. Mol Cell Biol 19(4):3184-97 {{SGDpaper|S000054483}} PMID 10082585</ref><ref name='S000125665'>Bugnicourt A, et al. (2008) Irs4p and Tax4p: two redundant EH domain proteins involved in autophagy. Traffic 9(5):755-69
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'''Description of YKR019C:''' EH domain-containing protein involved in regulating phosphatidylinositol 4,5-bisphosphate levels and autophagy; Irs4p and Tax4p bind and activate the PtdIns phosphatase Inp51p; Irs4p and Tax4p are involved in localizing Atg17p to the PAS<ref name='S000125665'>Bugnicourt A, et al. (2008) Irs4p and Tax4p: two redundant EH domain proteins involved in autophagy. Traffic 9(5):755-69 {{SGDpaper|S000125665}} PMID 18298591</ref><ref name='S000040062'>Paoluzi S, et al. (1998) Recognition specificity of individual EH domains of mammals and yeast. EMBO J 17(22):6541-50 {{SGDpaper|S000040062}} PMID 9822599</ref><ref name='S000054483'>Smith JS, et al. (1999) A genetic screen for ribosomal DNA silencing defects identifies multiple DNA replication and chromatin-modulating factors. Mol Cell Biol 19(4):3184-97
{{SGDpaper|S000125665}} PMID 18298591</ref>
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{{SGDpaper|S000054483}} PMID 10082585</ref>
 
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Revision as of 14:05, 25 February 2010

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Systematic name YKR019C
Gene name IRS4
Aliases
Feature type ORF, Verified
Coordinates Chr XI:477706..475859
Primary SGDID S000001727


Description of YKR019C: EH domain-containing protein involved in regulating phosphatidylinositol 4,5-bisphosphate levels and autophagy; Irs4p and Tax4p bind and activate the PtdIns phosphatase Inp51p; Irs4p and Tax4p are involved in localizing Atg17p to the PAS[1][2][3]




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References

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  1. Bugnicourt A, et al. (2008) Irs4p and Tax4p: two redundant EH domain proteins involved in autophagy. Traffic 9(5):755-69 SGD PMID 18298591
  2. Paoluzi S, et al. (1998) Recognition specificity of individual EH domains of mammals and yeast. EMBO J 17(22):6541-50 SGD PMID 9822599
  3. Smith JS, et al. (1999) A genetic screen for ribosomal DNA silencing defects identifies multiple DNA replication and chromatin-modulating factors. Mol Cell Biol 19(4):3184-97 SGD PMID 10082585

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