Difference between revisions of "YKR019C"
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| − | '''Description of YKR019C:''' | + | '''Description of YKR019C:''' EH domain-containing protein involved in regulating phosphatidylinositol 4,5-bisphosphate levels and autophagy; Irs4p and Tax4p bind and activate the PtdIns phosphatase Inp51p; Irs4p and Tax4p are involved in localizing Atg17p to the PAS<ref name='S000125665'>Bugnicourt A, et al. (2008) Irs4p and Tax4p: Two Redundant EH Domain Proteins Involved in Autophagy. Traffic {{SGDpaper|S000125665}} PMID 18298591</ref><ref name='S000054483'>Smith JS, et al. (1999) A genetic screen for ribosomal DNA silencing defects identifies multiple DNA replication and chromatin-modulating factors. Mol Cell Biol 19(4):3184-97 {{SGDpaper|S000054483}} PMID 10082585</ref><ref name='S000040062'>Paoluzi S, et al. (1998) Recognition specificity of individual EH domains of mammals and yeast. EMBO J 17(22):6541-50 |
| − | {{SGDpaper| | + | {{SGDpaper|S000040062}} PMID 9822599</ref> |
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Revision as of 14:05, 15 April 2008
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| Systematic name | YKR019C |
| Gene name | IRS4 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:477706..475859 |
| Primary SGDID | S000001727 |
Description of YKR019C: EH domain-containing protein involved in regulating phosphatidylinositol 4,5-bisphosphate levels and autophagy; Irs4p and Tax4p bind and activate the PtdIns phosphatase Inp51p; Irs4p and Tax4p are involved in localizing Atg17p to the PAS[1][2][3]
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References
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- ↑ Bugnicourt A, et al. (2008) Irs4p and Tax4p: Two Redundant EH Domain Proteins Involved in Autophagy. Traffic SGD PMID 18298591
- ↑ Smith JS, et al. (1999) A genetic screen for ribosomal DNA silencing defects identifies multiple DNA replication and chromatin-modulating factors. Mol Cell Biol 19(4):3184-97 SGD PMID 10082585
- ↑ Paoluzi S, et al. (1998) Recognition specificity of individual EH domains of mammals and yeast. EMBO J 17(22):6541-50 SGD PMID 9822599
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