YKR001C

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Systematic name YKR001C
Gene name VPS1
Aliases GRD1, LAM1, SPO15, VPL1, VPT26
Feature type ORF, Verified
Coordinates Chr XI:442365..440251


Description of YKR001C: GTPase required for vacuolar protein sorting, functions in actin cytoskeleton organization via its interaction with Sla1p; required for late Golgi-retention of some proteins including Kex2p; involved in regulating peroxisome biogenesis[1][2][3][4]




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References

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  1. Yu X and Cai M (2004) The yeast dynamin-related GTPase Vps1p functions in the organization of the actin cytoskeleton via interaction with Sla1p. J Cell Sci 117(Pt 17):3839-53 SGD PMID 15265985
  2. Vizeacoumar FJ, et al. (2003) YHR150w and YDR479c encode peroxisomal integral membrane proteins involved in the regulation of peroxisome number, size, and distribution in Saccharomyces cerevisiae. J Cell Biol 161(2):321-32 SGD PMID 12707309
  3. Nothwehr SF, et al. (1996) The newly identified yeast GRD genes are required for retention of late-Golgi membrane proteins. Mol Cell Biol 16(6):2700-7 SGD PMID 8649377
  4. Ekena K, et al. (1993) The VPS1 protein is a dynamin-like GTPase required for sorting proteins to the yeast vacuole. Ciba Found Symp 176():198-211; discussion 211-4 SGD PMID 8299420

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