YKL220C

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Systematic name YKL220C
Gene name FRE2
Aliases
Feature type ORF, Verified
Coordinates Chr XI:11226..9091
Primary SGDID S000001703


Description of YKL220C: Ferric reductase and cupric reductase, reduces siderophore-bound iron and oxidized copper prior to uptake by transporters; expression induced by low iron levels but not by low copper levels[1][2][3]




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References

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  1. Georgatsou E and Alexandraki D (1999) Regulated expression of the Saccharomyces cerevisiae Fre1p/Fre2p Fe/Cu reductase related genes. Yeast 15(7):573-84 SGD PMID 10341420
  2. Georgatsou E, et al. (1997) The yeast Fre1p/Fre2p cupric reductases facilitate copper uptake and are regulated by the copper-modulated Mac1p activator. J Biol Chem 272(21):13786-92 SGD PMID 9153234
  3. Yun CW, et al. (2001) The role of the FRE family of plasma membrane reductases in the uptake of siderophore-iron in Saccharomyces cerevisiae. J Biol Chem 276(13):10218-23 SGD PMID 11120744

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