Difference between revisions of "YKL217W"

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'''Description of YKL217W:''' Lactate transporter, required for uptake of lactate and pyruvate; expression is derepressed by transcriptional activator Cat8p under nonfermentative growth conditions, and repressed in the presence of glucose, fructose, and mannose<ref name='S000056432'>Akita O, et al. (2000) Transport of pyruvate in Saccharomyces cerevisiae and cloning of the gene encoded pyruvate permease. Biosci Biotechnol Biochem 64(5):980-4 {{SGDpaper|S000056432}} PMID 10879467</ref><ref name='S000053081'>Casal M, et al. (1999) The lactate-proton symport of Saccharomyces cerevisiae is encoded by JEN1. J Bacteriol 181(8):2620-3 {{SGDpaper|S000053081}} PMID 10198029</ref><ref name='S000043068'>Haurie V, et al. (2001) The transcriptional activator Cat8p provides a major contribution to the reprogramming of carbon metabolism during the diauxic shift in Saccharomyces cerevisiae. J Biol Chem 276(1):76-85
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'''Description of YKL217W:''' Lactate transporter, required for uptake of lactate and pyruvate; phosphorylated; expression is derepressed by transcriptional activator Cat8p during respiratory growth, and repressed in the presence of glucose, fructose, and mannose<ref name='S000123951'>Reinders J, et al. (2007) Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Mol Cell Proteomics  {{SGDpaper|S000123951}} PMID 17761666</ref><ref name='S000056432'>Akita O, et al. (2000) Transport of pyruvate in Saccharomyces cerevisiae and cloning of the gene encoded pyruvate permease. Biosci Biotechnol Biochem 64(5):980-4 {{SGDpaper|S000056432}} PMID 10879467</ref><ref name='S000053081'>Casal M, et al. (1999) The lactate-proton symport of Saccharomyces cerevisiae is encoded by JEN1. J Bacteriol 181(8):2620-3 {{SGDpaper|S000053081}} PMID 10198029</ref><ref name='S000043068'>Haurie V, et al. (2001) The transcriptional activator Cat8p provides a major contribution to the reprogramming of carbon metabolism during the diauxic shift in Saccharomyces cerevisiae. J Biol Chem 276(1):76-85
 
  {{SGDpaper|S000043068}} PMID 11024040</ref>
 
  {{SGDpaper|S000043068}} PMID 11024040</ref>
 
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Revision as of 14:05, 18 September 2007

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Systematic name YKL217W
Gene name JEN1
Aliases
Feature type ORF, Verified
Coordinates Chr XI:22234..24084
Primary SGDID S000001700


Description of YKL217W: Lactate transporter, required for uptake of lactate and pyruvate; phosphorylated; expression is derepressed by transcriptional activator Cat8p during respiratory growth, and repressed in the presence of glucose, fructose, and mannose[1][2][3][4]




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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically lower expression in sulfur limited chemostat cultures versus sulfur excess. [5] [6]


Other Topic: expression

Specifically higher expression in carbon limited chemostat cultures versus carbon excess. [5] [6]





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References

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  1. Reinders J, et al. (2007) Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Mol Cell Proteomics SGD PMID 17761666
  2. Akita O, et al. (2000) Transport of pyruvate in Saccharomyces cerevisiae and cloning of the gene encoded pyruvate permease. Biosci Biotechnol Biochem 64(5):980-4 SGD PMID 10879467
  3. Casal M, et al. (1999) The lactate-proton symport of Saccharomyces cerevisiae is encoded by JEN1. J Bacteriol 181(8):2620-3 SGD PMID 10198029
  4. Haurie V, et al. (2001) The transcriptional activator Cat8p provides a major contribution to the reprogramming of carbon metabolism during the diauxic shift in Saccharomyces cerevisiae. J Biol Chem 276(1):76-85 SGD PMID 11024040
  5. 5.0 5.1 Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  6. 6.0 6.1 submitted by Viktor Boer on 2003-07-25

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