Difference between revisions of "YKL209C"

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'''Description of YKL209C:''' ATP-binding cassette (ABC) transporter required for the export of a-factor, catalyzes ATP hydrolysis coupled to a-factor transport, contains 12 transmembrane domains and two ATP binding domains, expressed only in MATa cells<ref name='S000065827'>Ketchum CJ, et al. (2001) The yeast a-factor transporter Ste6p, a member of the ABC superfamily, couples ATP hydrolysis to pheromone export. J Biol Chem 276(31):29007-11 {{SGDpaper|S000065827}} PMID 11389139</ref><ref name='S000052762'>Loayza D and Michaelis S (1998) Role for the ubiquitin-proteasome system in the vacuolar degradation of Ste6p, the a-factor transporter in Saccharomyces cerevisiae. Mol Cell Biol 18(2):779-89 {{SGDpaper|S000052762}} PMID 9447974</ref><ref name='S000052433'>Kuchler K, et al. (1989) Saccharomyces cerevisiae STE6 gene product: a novel pathway for protein export in eukaryotic cells. EMBO J 8(13):3973-84 {{SGDpaper|S000052433}} PMID 2686977</ref><ref name='S000040545'>McGrath JP and Varshavsky A (1989) The yeast STE6 gene encodes a homologue of the mammalian multidrug resistance P-glycoprotein. Nature 340(6232):400-4
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'''Description of YKL209C:''' Plasma membrane ATP-binding cassette (ABC) transporter required for the export of a-factor, catalyzes ATP hydrolysis coupled to a-factor transport, contains 12 transmembrane domains and two ATP binding domains, expressed only in MATa cells<ref name='S000065827'>Ketchum CJ, et al. (2001) The yeast a-factor transporter Ste6p, a member of the ABC superfamily, couples ATP hydrolysis to pheromone export. J Biol Chem 276(31):29007-11 {{SGDpaper|S000065827}} PMID 11389139</ref><ref name='S000052762'>Loayza D and Michaelis S (1998) Role for the ubiquitin-proteasome system in the vacuolar degradation of Ste6p, the a-factor transporter in Saccharomyces cerevisiae. Mol Cell Biol 18(2):779-89 {{SGDpaper|S000052762}} PMID 9447974</ref><ref name='S000052433'>Kuchler K, et al. (1989) Saccharomyces cerevisiae STE6 gene product: a novel pathway for protein export in eukaryotic cells. EMBO J 8(13):3973-84 {{SGDpaper|S000052433}} PMID 2686977</ref><ref name='S000052426'>Michaelis S (1993) STE6, the yeast a-factor transporter. Semin Cell Biol 4(1):17-27 {{SGDpaper|S000052426}} PMID 8095825</ref><ref name='S000040545'>McGrath JP and Varshavsky A (1989) The yeast STE6 gene encodes a homologue of the mammalian multidrug resistance P-glycoprotein. Nature 340(6232):400-4
 
  {{SGDpaper|S000040545}} PMID 2569166</ref>
 
  {{SGDpaper|S000040545}} PMID 2569166</ref>
 
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Revision as of 14:05, 15 August 2007

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Systematic name YKL209C
Gene name STE6
Aliases
Feature type ORF, Verified
Coordinates Chr XI:46296..42424
Primary SGDID S000001692


Description of YKL209C: Plasma membrane ATP-binding cassette (ABC) transporter required for the export of a-factor, catalyzes ATP hydrolysis coupled to a-factor transport, contains 12 transmembrane domains and two ATP binding domains, expressed only in MATa cells[1][2][3][4][5]




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DNA and RNA Details

Other DNA and RNA Details

Other Topic: expression

Specifically lower expression in carbon limited chemostat cultures versus carbon excess. [6] [7]





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References

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  1. Ketchum CJ, et al. (2001) The yeast a-factor transporter Ste6p, a member of the ABC superfamily, couples ATP hydrolysis to pheromone export. J Biol Chem 276(31):29007-11 SGD PMID 11389139
  2. Loayza D and Michaelis S (1998) Role for the ubiquitin-proteasome system in the vacuolar degradation of Ste6p, the a-factor transporter in Saccharomyces cerevisiae. Mol Cell Biol 18(2):779-89 SGD PMID 9447974
  3. Kuchler K, et al. (1989) Saccharomyces cerevisiae STE6 gene product: a novel pathway for protein export in eukaryotic cells. EMBO J 8(13):3973-84 SGD PMID 2686977
  4. Michaelis S (1993) STE6, the yeast a-factor transporter. Semin Cell Biol 4(1):17-27 SGD PMID 8095825
  5. McGrath JP and Varshavsky A (1989) The yeast STE6 gene encodes a homologue of the mammalian multidrug resistance P-glycoprotein. Nature 340(6232):400-4 SGD PMID 2569166
  6. Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
  7. submitted by Viktor Boer on 2003-07-25

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