Difference between revisions of "YKL203C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YKL203C YKL203C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001686 YKL203C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''TOR2 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''TOR2 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
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|nowrap| Chr XI:63360..55936
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|nowrap| Chr XI:63359..55935
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001686
 
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'''Description of {{PAGENAME}}:''' PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that regulates growth in response to nutrients and TORC2, a complex that regulates cell-cycle dependent polarization of the actin cytoskeleton; involved in meiosis<ref name='S000080060'>Martin DE, et al. (2004) TOR regulates ribosomal protein gene expression via PKA and the Forkhead transcription factor FHL1. Cell 119(7):969-79 {{SGDpaper|S000080060}} PMID 15620355</ref><ref name='S000077468'>Lorberg A and Hall MN (2004) TOR: the first 10 years. Curr Top Microbiol Immunol 279():1-18 {{SGDpaper|S000077468}} PMID 14560948</ref><ref name='S000071617'>Torres J, et al. (2002) Regulation of the cell integrity pathway by rapamycin-sensitive TOR function in budding yeast. J Biol Chem 277(45):43495-504 {{SGDpaper|S000071617}} PMID 12171921</ref><ref name='S000071528'>Loewith R, et al. (2002) Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control. Mol Cell 10(3):457-68 {{SGDpaper|S000071528}} PMID 12408816</ref><ref name='S000055222'>Cardenas ME, et al. (1999) The TOR signaling cascade regulates gene expression in response to nutrients. Genes Dev 13(24):3271-9 {{SGDpaper|S000055222}} PMID 10617575</ref><ref name='S000053128'>Powers T and Walter P (1999) Regulation of ribosome biogenesis by the rapamycin-sensitive TOR-signaling pathway in Saccharomyces cerevisiae. Mol Biol Cell 10(4):987-1000 {{SGDpaper|S000053128}} PMID 10198052</ref><ref name='S000046200'>Beck T and Hall MN (1999) The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factors. Nature 402(6762):689-92 {{SGDpaper|S000046200}} PMID 10604478</ref><ref name='S000042595'>Schmidt A, et al. (1996) TOR2 is required for organization of the actin cytoskeleton in yeast. Proc Natl Acad Sci U S A 93(24):13780-5 {{SGDpaper|S000042595}} PMID 8943012</ref><ref name='S000042312'>Kamada Y, et al. (2000) Tor-mediated induction of autophagy via an Apg1 protein kinase complex. J Cell Biol 150(6):1507-13 {{SGDpaper|S000042312}} PMID 10995454</ref><ref name='S000041984'>Zheng XF and Schreiber SL (1997) Target of rapamycin proteins and their kinase activities are required for meiosis. Proc Natl Acad Sci U S A 94(7):3070-5
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'''Description of YKL203C:''' PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that regulates growth in response to nutrients and TORC2, a complex that regulates cell-cycle dependent polarization of the actin cytoskeleton; involved in meiosis<ref name='S000046200'>Beck T and Hall MN (1999) The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factors. Nature 402(6762):689-92 {{SGDpaper|S000046200}} PMID 10604478</ref><ref name='S000055222'>Cardenas ME, et al. (1999) The TOR signaling cascade regulates gene expression in response to nutrients. Genes Dev 13(24):3271-9 {{SGDpaper|S000055222}} PMID 10617575</ref><ref name='S000042312'>Kamada Y, et al. (2000) Tor-mediated induction of autophagy via an Apg1 protein kinase complex. J Cell Biol 150(6):1507-13 {{SGDpaper|S000042312}} PMID 10995454</ref><ref name='S000071528'>Loewith R, et al. (2002) Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control. Mol Cell 10(3):457-68 {{SGDpaper|S000071528}} PMID 12408816</ref><ref name='S000077468'>Lorberg A and Hall MN (2004) TOR: the first 10 years. Curr Top Microbiol Immunol 279():1-18 {{SGDpaper|S000077468}} PMID 14560948</ref><ref name='S000080060'>Martin DE, et al. (2004) TOR regulates ribosomal protein gene expression via PKA and the Forkhead transcription factor FHL1. Cell 119(7):969-79 {{SGDpaper|S000080060}} PMID 15620355</ref><ref name='S000053128'>Powers T and Walter P (1999) Regulation of ribosome biogenesis by the rapamycin-sensitive TOR-signaling pathway in Saccharomyces cerevisiae. Mol Biol Cell 10(4):987-1000 {{SGDpaper|S000053128}} PMID 10198052</ref><ref name='S000042595'>Schmidt A, et al. (1996) TOR2 is required for organization of the actin cytoskeleton in yeast. Proc Natl Acad Sci U S A 93(24):13780-5 {{SGDpaper|S000042595}} PMID 8943012</ref><ref name='S000071617'>Torres J, et al. (2002) Regulation of the cell integrity pathway by rapamycin-sensitive TOR function in budding yeast. J Biol Chem 277(45):43495-504 {{SGDpaper|S000071617}} PMID 12171921</ref><ref name='S000041984'>Zheng XF and Schreiber SL (1997) Target of rapamycin proteins and their kinase activities are required for meiosis. Proc Natl Acad Sci U S A 94(7):3070-5
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YKL203C
Gene name TOR2
Aliases DRR2
Feature type ORF, Verified
Coordinates Chr XI:63359..55935
Primary SGDID S000001686


Description of YKL203C: PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that regulates growth in response to nutrients and TORC2, a complex that regulates cell-cycle dependent polarization of the actin cytoskeleton; involved in meiosis[1][2][3][4][5][6][7][8][9][10]




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References

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  1. ↑ Beck T and Hall MN (1999) The TOR signalling pathway controls nuclear localization of nutrient-regulated transcription factors. Nature 402(6762):689-92 SGD PMID 10604478
  2. ↑ Cardenas ME, et al. (1999) The TOR signaling cascade regulates gene expression in response to nutrients. Genes Dev 13(24):3271-9 SGD PMID 10617575
  3. ↑ Kamada Y, et al. (2000) Tor-mediated induction of autophagy via an Apg1 protein kinase complex. J Cell Biol 150(6):1507-13 SGD PMID 10995454
  4. ↑ Loewith R, et al. (2002) Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control. Mol Cell 10(3):457-68 SGD PMID 12408816
  5. ↑ Lorberg A and Hall MN (2004) TOR: the first 10 years. Curr Top Microbiol Immunol 279():1-18 SGD PMID 14560948
  6. ↑ Martin DE, et al. (2004) TOR regulates ribosomal protein gene expression via PKA and the Forkhead transcription factor FHL1. Cell 119(7):969-79 SGD PMID 15620355
  7. ↑ Powers T and Walter P (1999) Regulation of ribosome biogenesis by the rapamycin-sensitive TOR-signaling pathway in Saccharomyces cerevisiae. Mol Biol Cell 10(4):987-1000 SGD PMID 10198052
  8. ↑ Schmidt A, et al. (1996) TOR2 is required for organization of the actin cytoskeleton in yeast. Proc Natl Acad Sci U S A 93(24):13780-5 SGD PMID 8943012
  9. ↑ Torres J, et al. (2002) Regulation of the cell integrity pathway by rapamycin-sensitive TOR function in budding yeast. J Biol Chem 277(45):43495-504 SGD PMID 12171921
  10. ↑ Zheng XF and Schreiber SL (1997) Target of rapamycin proteins and their kinase activities are required for meiosis. Proc Natl Acad Sci U S A 94(7):3070-5 SGD PMID 9096347

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