Difference between revisions of "YKL195W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YKL195W YKL195W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001678 YKL195W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MIA40 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MIA40 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr XI:75826..77037
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|nowrap| Chr XI:75821..77032
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000001678
 
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'''Description of {{PAGENAME}}:''' Essential protein of the mitochondrial intermembrane space (IMS); promotes retention of newly imported proteins; may do so by stabilizing client protein folding as part of a disulfide relay system or transferring metal to client proteins<ref name='S000086368'>Mesecke N, et al. (2005) A disulfide relay system in the intermembrane space of mitochondria that mediates protein import. Cell 121(7):1059-69 {{SGDpaper|S000086368}} PMID 15989955</ref><ref name='S000080801'>Terziyska N, et al. (2005) Mia40, a novel factor for protein import into the intermembrane space of mitochondria is able to bind metal ions. FEBS Lett 579(1):179-84 {{SGDpaper|S000080801}} PMID 15620710</ref><ref name='S000077205'>Chacinska A, et al. (2004) Essential role of Mia40 in import and assembly of mitochondrial intermembrane space proteins. EMBO J 23(19):3735-46
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'''Description of YKL195W:''' Essential protein of the mitochondrial intermembrane space (IMS); promotes retention of newly imported proteins; may do so by stabilizing client protein folding as part of a disulfide relay system or transferring metal to client proteins<ref name='S000077205'>Chacinska A, et al. (2004) Essential role of Mia40 in import and assembly of mitochondrial intermembrane space proteins. EMBO J 23(19):3735-46 {{SGDpaper|S000077205}} PMID 15359280</ref><ref name='S000086368'>Mesecke N, et al. (2005) A disulfide relay system in the intermembrane space of mitochondria that mediates protein import. Cell 121(7):1059-69 {{SGDpaper|S000086368}} PMID 15989955</ref><ref name='S000080801'>Terziyska N, et al. (2005) Mia40, a novel factor for protein import into the intermembrane space of mitochondria is able to bind metal ions. FEBS Lett 579(1):179-84
{{SGDpaper|S000077205}} PMID 15359280</ref>
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{{SGDpaper|S000080801}} PMID 15620710</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YKL195W
Gene name MIA40
Aliases FMP15, TIM40
Feature type ORF, Verified
Coordinates Chr XI:75821..77032
Primary SGDID S000001678


Description of YKL195W: Essential protein of the mitochondrial intermembrane space (IMS); promotes retention of newly imported proteins; may do so by stabilizing client protein folding as part of a disulfide relay system or transferring metal to client proteins[1][2][3]




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References

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  1. Chacinska A, et al. (2004) Essential role of Mia40 in import and assembly of mitochondrial intermembrane space proteins. EMBO J 23(19):3735-46 SGD PMID 15359280
  2. Mesecke N, et al. (2005) A disulfide relay system in the intermembrane space of mitochondria that mediates protein import. Cell 121(7):1059-69 SGD PMID 15989955
  3. Terziyska N, et al. (2005) Mia40, a novel factor for protein import into the intermembrane space of mitochondria is able to bind metal ions. FEBS Lett 579(1):179-84 SGD PMID 15620710

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