Difference between revisions of "YKL195W"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001678 YKL195W]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000001678 YKL195W]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MIA40 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''MIA40 ''

Latest revision as of 07:45, 23 January 2012

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Systematic name YKL195W
Gene name MIA40
Aliases FMP15, TIM40
Feature type ORF, Verified
Coordinates Chr XI:75821..77032
Primary SGDID S000001678


Description of YKL195W: Essential protein of the mitochondrial intermembrane space (IMS); promotes retention of newly imported proteins; may do so by stabilizing client protein folding as part of a disulfide relay system or transferring metal to client proteins[1][2][3]




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References

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  1. Chacinska A, et al. (2004) Essential role of Mia40 in import and assembly of mitochondrial intermembrane space proteins. EMBO J 23(19):3735-46 SGD PMID 15359280
  2. Mesecke N, et al. (2005) A disulfide relay system in the intermembrane space of mitochondria that mediates protein import. Cell 121(7):1059-69 SGD PMID 15989955
  3. Terziyska N, et al. (2005) Mia40, a novel factor for protein import into the intermembrane space of mitochondria is able to bind metal ions. FEBS Lett 579(1):179-84 SGD PMID 15620710

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