YKL126W

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Systematic name YKL126W
Gene name YPK1
Aliases SLI2
Feature type ORF, Verified
Coordinates Chr XI:205351..207393
Primary SGDID S000001609


Description of YKL126W: Serine/threonine protein kinase required for receptor-mediated endocytosis; involved in sphingolipid-mediated and cell integrity signaling pathways; localized to the bud neck, cytosol and plasma membrane; homolog of mammalian kinase SGK[1][2][3]




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References

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  1. Sun Y, et al. (2000) Sli2 (Ypk1), a homologue of mammalian protein kinase SGK, is a downstream kinase in the sphingolipid-mediated signaling pathway of yeast. Mol Cell Biol 20(12):4411-9 SGD PMID 10825204
  2. deHart AK, et al. (2002) The conserved Pkh-Ypk kinase cascade is required for endocytosis in yeast. J Cell Biol 156(2):241-8 SGD PMID 11807089
  3. Schmelzle T, et al. (2002) Yeast protein kinases and the RHO1 exchange factor TUS1 are novel components of the cell integrity pathway in yeast. Mol Cell Biol 22(5):1329-39 SGD PMID 11839800

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