Difference between revisions of "YKL114C"
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==Community Commentary== | ==Community Commentary== | ||
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Revision as of 08:18, 30 January 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YKL114C |
| Gene name | APN1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:224099..222996 |
Description of YKL114C: Major apurinic/apyrimidinic endonuclease, 3'-repair diesterase involved in repair of DNA damage by oxidation and alkylating agents; also functions as a 3'-5' exonuclease to repair 7,8-dihydro-8-oxodeoxyguanosine[1][2][3]
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Contents
Community Commentary
About Community Commentary. Please share your knowledge!
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References
See Help:References on how to add references
- ↑ Ishchenko AA, et al. (2005) The 3'->5' exonuclease of Apn1 provides an alternative pathway to repair 7,8-dihydro-8-oxodeoxyguanosine in Saccharomyces cerevisiae. Mol Cell Biol 25(15):6380-90 SGD PMID 16024777
- ↑ Ramotar D, et al. (1991) Cellular role of yeast Apn1 apurinic endonuclease/3'-diesterase: repair of oxidative and alkylation DNA damage and control of spontaneous mutation. Mol Cell Biol 11(9):4537-44 SGD PMID 1715020
- ↑ Popoff SC, et al. (1990) Yeast structural gene (APN1) for the major apurinic endonuclease: homology to Escherichia coli endonuclease IV. Proc Natl Acad Sci U S A 87(11):4193-7 SGD PMID 1693433
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