Difference between revisions of "YKL108W"
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
|nowrap| Chr XI:234070..235431 | |nowrap| Chr XI:234070..235431 | ||
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==Community Commentary== | ==Community Commentary== | ||
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Revision as of 08:18, 30 January 2007
Share your knowledge...Edit this entry! <protect>
| Systematic name | YKL108W |
| Gene name | SLD2 |
| Aliases | DRC1 |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:234070..235431 |
Description of YKL108W: Protein required for DNA replication, phosphorylated in S phase by S-phase cyclin-dependent kinases (Cdks), phosphorylation is essential for DNA replication and for complex formation with Dpb11p; potential Cdc28p substrate[1][2][3]
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Community Commentary
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [1] [4]
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References
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- ↑ 1.0 1.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ Masumoto H, et al. (2002) S-Cdk-dependent phosphorylation of Sld2 essential for chromosomal DNA replication in budding yeast. Nature 415(6872):651-5 SGD PMID 11807498
- ↑ Kamimura Y, et al. (1998) Sld2, which interacts with Dpb11 in Saccharomyces cerevisiae, is required for chromosomal DNA replication. Mol Cell Biol 18(10):6102-9 SGD PMID 9742127
- ↑ submitted by Jeff Ubersax on 2004-01-27
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