Difference between revisions of "YKL088W"
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| − | '''Description of YKL088W:''' | + | '''Description of YKL088W:''' Subunit of a phosphopantothenoylcysteine decarboxylase (PPCDC; Cab3p, Sis2p, Vhs3p) complex, which catalyzes the third step of coenzyme A biosynthesis; null mutant lethality is complemented by E. coli coaBC<ref name='S000072463'>Tatusov RL, et al. (2000) The COG database: a tool for genome-scale analysis of protein functions and evolution. Nucleic Acids Res 28(1):33-6 {{SGDpaper|S000072463}} PMID 10592175</ref><ref name='S000075214'>Hazbun TR, et al. (2003) Assigning function to yeast proteins by integration of technologies. Mol Cell 12(6):1353-65 {{SGDpaper|S000075214}} PMID 14690591</ref><ref name='S000132230'>Ruiz A, et al. (2009) Moonlighting proteins Hal3 and Vhs3 form a heteromeric PPCDC with Ykl088w in yeast CoA biosynthesis. Nat Chem Biol 5(12):920-8 {{SGDpaper|S000132230}} PMID 19915539</ref><ref name='S000129524'>Olzhausen J, et al. (2009) Genetic analysis of coenzyme A biosynthesis in the yeast Saccharomyces cerevisiae: identification of a conditional mutation in the pantothenate kinase gene CAB1. Curr Genet 55(2):163-73 |
{{SGDpaper|S000129524}} PMID 19266201</ref> | {{SGDpaper|S000129524}} PMID 19266201</ref> | ||
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Revision as of 14:05, 18 December 2009
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| Systematic name | YKL088W |
| Gene name | CAB3 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XI:274927..276642 |
| Primary SGDID | S000001571 |
Description of YKL088W: Subunit of a phosphopantothenoylcysteine decarboxylase (PPCDC; Cab3p, Sis2p, Vhs3p) complex, which catalyzes the third step of coenzyme A biosynthesis; null mutant lethality is complemented by E. coli coaBC[1][2][3][4]
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References
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- ↑ Tatusov RL, et al. (2000) The COG database: a tool for genome-scale analysis of protein functions and evolution. Nucleic Acids Res 28(1):33-6 SGD PMID 10592175
- ↑ Hazbun TR, et al. (2003) Assigning function to yeast proteins by integration of technologies. Mol Cell 12(6):1353-65 SGD PMID 14690591
- ↑ Ruiz A, et al. (2009) Moonlighting proteins Hal3 and Vhs3 form a heteromeric PPCDC with Ykl088w in yeast CoA biosynthesis. Nat Chem Biol 5(12):920-8 SGD PMID 19915539
- ↑ Olzhausen J, et al. (2009) Genetic analysis of coenzyme A biosynthesis in the yeast Saccharomyces cerevisiae: identification of a conditional mutation in the pantothenate kinase gene CAB1. Curr Genet 55(2):163-73 SGD PMID 19266201
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