Difference between revisions of "YJR135W-A"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?dbid=S000007348 YJR135W-A]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000007348 YJR135W-A]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''TIM8 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''TIM8 ''

Latest revision as of 07:45, 23 January 2012

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Systematic name YJR135W-A
Gene name TIM8
Aliases
Feature type ORF, Verified
Coordinates Chr X:676971..677234
Primary SGDID S000007348


Description of YJR135W-A: Mitochondrial intermembrane space protein, forms a complex with Tim13p that delivers a subset of hydrophobic proteins to the TIM22 complex for inner membrane insertion; homolog of human TIMM8A, implicated in Mohr-Tranebjaerg syndrome[1][2][3][4]




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References

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  1. Bauer MF and Neupert W (2001) Import of proteins into mitochondria: a novel pathomechanism for progressive neurodegeneration. J Inherit Metab Dis 24(2):166-80 SGD PMID 11405338
  2. Davis AJ, et al. (2007) The Tim9p/10p and Tim8p/13p complexes bind to specific sites on Tim23p during mitochondrial protein import. Mol Biol Cell 18(2):475-86 SGD PMID 17122363
  3. Koehler CM, et al. (1999) Human deafness dystonia syndrome is a mitochondrial disease. Proc Natl Acad Sci U S A 96(5):2141-6 SGD PMID 10051608
  4. Leuenberger D, et al. (1999) Different import pathways through the mitochondrial intermembrane space for inner membrane proteins. EMBO J 18(17):4816-22 SGD PMID 10469659

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