Difference between revisions of "YJR135C"

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'''Description of YJR135C:''' Protein involved in minichromosome maintenance; component of the kinetochore which binds to centromeric DNA in a Ctf19p-dependent manner; orthologous to human centromere constitutive-associated network (CCAN) subunit CENP-K and fission yeast sim4<ref name='S000069067'>Measday V, et al. (2002) Ctf3p, the Mis6 budding yeast homolog, interacts with Mcm22p and Mcm16p at the yeast outer kinetochore. Genes Dev 16(1):101-13 {{SGDpaper|S000069067}} PMID 11782448</ref><ref name='S000054154'>Poddar A, et al. (1999) MCM21 and MCM22, two novel genes of the yeast Saccharomyces cerevisiae are required for chromosome transmission. Mol Microbiol 31(1):349-60 {{SGDpaper|S000054154}} PMID 9987135</ref><ref name='S000149670'>Schleiffer A, et al. (2012) CENP-T proteins are conserved centromere receptors of the Ndc80 complex. Nat Cell Biol 14(6):604-13
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'''Description of YJR135C:''' Outer kinetochore protein and component of the Ctf3 subcomplex; binds to centromeric DNA in a Ctf19p-dependent manner; involved in chromosome segregation and minichromosome maintenance; orthologous to human centromere constitutive-associated network (CCAN) subunit CENP-K and fission yeast sim4<ref name='S000069067'>Measday V, et al. (2002) Ctf3p, the Mis6 budding yeast homolog, interacts with Mcm22p and Mcm16p at the yeast outer kinetochore. Genes Dev 16(1):101-13 {{SGDpaper|S000069067}} PMID 11782448</ref><ref name='S000054154'>Poddar A, et al. (1999) MCM21 and MCM22, two novel genes of the yeast Saccharomyces cerevisiae are required for chromosome transmission. Mol Microbiol 31(1):349-60 {{SGDpaper|S000054154}} PMID 9987135</ref><ref name='S000149670'>Schleiffer A, et al. (2012) CENP-T proteins are conserved centromere receptors of the Ndc80 complex. Nat Cell Biol 14(6):604-13
 
  {{SGDpaper|S000149670}} PMID 22561346</ref>
 
  {{SGDpaper|S000149670}} PMID 22561346</ref>
 
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Latest revision as of 14:05, 9 October 2012

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Systematic name YJR135C
Gene name MCM22
Aliases
Feature type ORF, Verified
Coordinates Chr X:676778..676059
Primary SGDID S000003896


Description of YJR135C: Outer kinetochore protein and component of the Ctf3 subcomplex; binds to centromeric DNA in a Ctf19p-dependent manner; involved in chromosome segregation and minichromosome maintenance; orthologous to human centromere constitutive-associated network (CCAN) subunit CENP-K and fission yeast sim4[1][2][3]




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References

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  1. Measday V, et al. (2002) Ctf3p, the Mis6 budding yeast homolog, interacts with Mcm22p and Mcm16p at the yeast outer kinetochore. Genes Dev 16(1):101-13 SGD PMID 11782448
  2. Poddar A, et al. (1999) MCM21 and MCM22, two novel genes of the yeast Saccharomyces cerevisiae are required for chromosome transmission. Mol Microbiol 31(1):349-60 SGD PMID 9987135
  3. Schleiffer A, et al. (2012) CENP-T proteins are conserved centromere receptors of the Ndc80 complex. Nat Cell Biol 14(6):604-13 SGD PMID 22561346

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