YJR132W

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Systematic name YJR132W
Gene name NMD5
Aliases KAP119
Feature type ORF, Verified
Coordinates Chr X:669522..672668
Primary SGDID S000003893


Description of YJR132W: Karyopherin, a carrier protein involved in nuclear import of proteins; importin beta homolog[1][2][3]




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Community Commentary

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Interactions

Two Hybrid

Two Hybrid interaction with NAM7
Yeast Two-Hybrid screen with Upf1p as bait identified several interacting proteins [4] [5]





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References

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  1. Albertini M, et al. (1998) A novel nuclear import pathway for the transcription factor TFIIS. J Cell Biol 143(6):1447-55 SGD PMID 9852143
  2. Ferrigno P, et al. (1998) Regulated nucleo/cytoplasmic exchange of HOG1 MAPK requires the importin beta homologs NMD5 and XPO1. EMBO J 17(19):5606-14 SGD PMID 9755161
  3. Polizotto RS and Cyert MS (2001) Calcineurin-dependent nuclear import of the transcription factor Crz1p requires Nmd5p. J Cell Biol 154(5):951-60 SGD PMID 11535618
  4. He F and Jacobson A (1995) Identification of a novel component of the nonsense-mediated mRNA decay pathway by use of an interacting protein screen. Genes Dev 9(4):437-54 SGD PMID 7883168
  5. submitted by Jurgen Wittmann on 2003-04-30

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