YJR090C

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Systematic name YJR090C
Gene name GRR1
Aliases CAT80, COT2, SDC1, SSU2
Feature type ORF, Verified
Coordinates Chr X:594320..590865


Description of YJR090C: F-box protein component of the SCF ubiquitin-ligase complex, required for Cln1p and Cln2p degradation; involved in carbon catabolite repression, glucose-dependent divalent cation transport, high-affinity glucose transport, and morphogenesis[1][2][3][4][5][6][7]




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References

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  1. Flick JS and Johnston M (1991) GRR1 of Saccharomyces cerevisiae is required for glucose repression and encodes a protein with leucine-rich repeats. Mol Cell Biol 11(10):5101-12 SGD PMID 1922034
  2. Barral Y, et al. (1995) G1 cyclin turnover and nutrient uptake are controlled by a common pathway in yeast. Genes Dev 9(4):399-409 SGD PMID 7883165
  3. Conklin DS, et al. (1993) The COT2 gene is required for glucose-dependent divalent cation transport in Saccharomyces cerevisiae. Mol Cell Biol 13(4):2041-9 SGD PMID 8455597
  4. Li FN and Johnston M (1997) Grr1 of Saccharomyces cerevisiae is connected to the ubiquitin proteolysis machinery through Skp1: coupling glucose sensing to gene expression and the cell cycle. EMBO J 16(18):5629-38 SGD PMID 9312022
  5. Vallier LG, et al. (1994) Altered regulatory responses to glucose are associated with a glucose transport defect in grr1 mutants of Saccharomyces cerevisiae. Genetics 136(4):1279-85 SGD PMID 8013905
  6. Erickson JR and Johnston M (1994) Suppressors reveal two classes of glucose repression genes in the yeast Saccharomyces cerevisiae. Genetics 136(4):1271-8 SGD PMID 8013904
  7. Kim YJ, et al. (1994) Control of cellular morphogenesis by the Ip12/Bem2 GTPase-activating protein: possible role of protein phosphorylation. J Cell Biol 127(5):1381-94 SGD PMID 7962097

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