Difference between revisions of "YJR090C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YJR090C YJR090C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003850 YJR090C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''GRR1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''GRR1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr X:594320..590865
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|nowrap| Chr X:594327..590872
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003850
 
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'''Description of {{PAGENAME}}:''' F-box protein component of the SCF ubiquitin-ligase complex, required for Cln1p and Cln2p degradation; involved in carbon catabolite repression, glucose-dependent divalent cation transport, high-affinity glucose transport, and morphogenesis<ref name='S000045971'>Flick JS and Johnston M (1991) GRR1 of Saccharomyces cerevisiae is required for glucose repression and encodes a protein with leucine-rich repeats. Mol Cell Biol 11(10):5101-12 {{SGDpaper|S000045971}} PMID 1922034</ref><ref name='S000042822'>Barral Y, et al. (1995) G1 cyclin turnover and nutrient uptake are controlled by a common pathway in yeast. Genes Dev 9(4):399-409 {{SGDpaper|S000042822}} PMID 7883165</ref><ref name='S000042066'>Conklin DS, et al. (1993) The COT2 gene is required for glucose-dependent divalent cation transport in Saccharomyces cerevisiae. Mol Cell Biol 13(4):2041-9 {{SGDpaper|S000042066}} PMID 8455597</ref><ref name='S000040835'>Li FN and Johnston M (1997) Grr1 of Saccharomyces cerevisiae is connected to the ubiquitin proteolysis machinery through Skp1: coupling glucose sensing to gene expression and the cell cycle. EMBO J 16(18):5629-38 {{SGDpaper|S000040835}} PMID 9312022</ref><ref name='S000040282'>Vallier LG, et al. (1994) Altered regulatory responses to glucose are associated with a glucose transport defect in grr1 mutants of Saccharomyces cerevisiae. Genetics 136(4):1279-85 {{SGDpaper|S000040282}} PMID 8013905</ref><ref name='S000040280'>Erickson JR and Johnston M (1994) Suppressors reveal two classes of glucose repression genes in the yeast Saccharomyces cerevisiae. Genetics 136(4):1271-8 {{SGDpaper|S000040280}} PMID 8013904</ref><ref name='S000039492'>Kim YJ, et al. (1994) Control of cellular morphogenesis by the Ip12/Bem2 GTPase-activating protein: possible role of protein phosphorylation. J Cell Biol 127(5):1381-94
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'''Description of YJR090C:''' F-box protein component of the SCF ubiquitin-ligase complex; involved in carbon catabolite repression, glucose-dependent divalent cation transport, high-affinity glucose transport, morphogenesis, and sulfite detoxification<ref name='S000045880'>Avram D and Bakalinsky AT (1996) Multicopy FZF1 (SUL1) suppresses the sulfite sensitivity but not the glucose derepression or aberrant cell morphology of a grr1 mutant of Saccharomyces cerevisiae. Genetics 144(2):511-21 {{SGDpaper|S000045880}} PMID 8889516</ref><ref name='S000042822'>Barral Y, et al. (1995) G1 cyclin turnover and nutrient uptake are controlled by a common pathway in yeast. Genes Dev 9(4):399-409 {{SGDpaper|S000042822}} PMID 7883165</ref><ref name='S000042066'>Conklin DS, et al. (1993) The COT2 gene is required for glucose-dependent divalent cation transport in Saccharomyces cerevisiae. Mol Cell Biol 13(4):2041-9 {{SGDpaper|S000042066}} PMID 8455597</ref><ref name='S000040280'>Erickson JR and Johnston M (1994) Suppressors reveal two classes of glucose repression genes in the yeast Saccharomyces cerevisiae. Genetics 136(4):1271-8 {{SGDpaper|S000040280}} PMID 8013904</ref><ref name='S000045971'>Flick JS and Johnston M (1991) GRR1 of Saccharomyces cerevisiae is required for glucose repression and encodes a protein with leucine-rich repeats. Mol Cell Biol 11(10):5101-12 {{SGDpaper|S000045971}} PMID 1922034</ref><ref name='S000039492'>Kim YJ, et al. (1994) Control of cellular morphogenesis by the Ip12/Bem2 GTPase-activating protein: possible role of protein phosphorylation. J Cell Biol 127(5):1381-94 {{SGDpaper|S000039492}} PMID 7962097</ref><ref name='S000040835'>Li FN and Johnston M (1997) Grr1 of Saccharomyces cerevisiae is connected to the ubiquitin proteolysis machinery through Skp1: coupling glucose sensing to gene expression and the cell cycle. EMBO J 16(18):5629-38 {{SGDpaper|S000040835}} PMID 9312022</ref><ref name='S000040282'>Vallier LG, et al. (1994) Altered regulatory responses to glucose are associated with a glucose transport defect in grr1 mutants of Saccharomyces cerevisiae. Genetics 136(4):1279-85
  {{SGDpaper|S000039492}} PMID 7962097</ref>
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  {{SGDpaper|S000040282}} PMID 8013905</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
{{CommentaryHelp}}
 
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<!-- PLEASE ADD Community Commentary ABOVE THIS MESSAGE. See below for an example of community annotation -->
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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Latest revision as of 07:45, 23 January 2012

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Systematic name YJR090C
Gene name GRR1
Aliases CAT80, COT2, SDC1, SSU2
Feature type ORF, Verified
Coordinates Chr X:594327..590872
Primary SGDID S000003850


Description of YJR090C: F-box protein component of the SCF ubiquitin-ligase complex; involved in carbon catabolite repression, glucose-dependent divalent cation transport, high-affinity glucose transport, morphogenesis, and sulfite detoxification[1][2][3][4][5][6][7][8]




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Community Commentary

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References

See Help:References on how to add references

  1. Avram D and Bakalinsky AT (1996) Multicopy FZF1 (SUL1) suppresses the sulfite sensitivity but not the glucose derepression or aberrant cell morphology of a grr1 mutant of Saccharomyces cerevisiae. Genetics 144(2):511-21 SGD PMID 8889516
  2. Barral Y, et al. (1995) G1 cyclin turnover and nutrient uptake are controlled by a common pathway in yeast. Genes Dev 9(4):399-409 SGD PMID 7883165
  3. Conklin DS, et al. (1993) The COT2 gene is required for glucose-dependent divalent cation transport in Saccharomyces cerevisiae. Mol Cell Biol 13(4):2041-9 SGD PMID 8455597
  4. Erickson JR and Johnston M (1994) Suppressors reveal two classes of glucose repression genes in the yeast Saccharomyces cerevisiae. Genetics 136(4):1271-8 SGD PMID 8013904
  5. Flick JS and Johnston M (1991) GRR1 of Saccharomyces cerevisiae is required for glucose repression and encodes a protein with leucine-rich repeats. Mol Cell Biol 11(10):5101-12 SGD PMID 1922034
  6. Kim YJ, et al. (1994) Control of cellular morphogenesis by the Ip12/Bem2 GTPase-activating protein: possible role of protein phosphorylation. J Cell Biol 127(5):1381-94 SGD PMID 7962097
  7. Li FN and Johnston M (1997) Grr1 of Saccharomyces cerevisiae is connected to the ubiquitin proteolysis machinery through Skp1: coupling glucose sensing to gene expression and the cell cycle. EMBO J 16(18):5629-38 SGD PMID 9312022
  8. Vallier LG, et al. (1994) Altered regulatory responses to glucose are associated with a glucose transport defect in grr1 mutants of Saccharomyces cerevisiae. Genetics 136(4):1279-85 SGD PMID 8013905

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