Difference between revisions of "YJR072C"
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{|{{Prettytable}} align = 'right' width = '200px' | {|{{Prettytable}} align = 'right' width = '200px' | ||
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| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http:// | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003833 YJR072C] |
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''NPA3 '' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name''' ||''NPA3 '' | ||
|- | |- | ||
| − | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||''EPA1'' | + | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Aliases''' ||''EPA1, GPN1'' |
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]] | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Feature type''' || ORF, Verified[[Category:ORF]][[Category:ORF, Verified]] | ||
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates''' | ||
| − | |nowrap| Chr X: | + | |nowrap| Chr X:572124..570967 |
|- | |- | ||
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003833 | |valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID''' || S000003833 | ||
|} | |} | ||
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| − | '''Description of YJR072C:''' | + | '''Description of YJR072C:''' Member of the conserved GPN-loop GTPase family; has a role in transport of RNA polymerase II to the nucleus; exhibits GTP-dependent binding to PolII; has ATPase activity; involved in sister chromatid cohesion; phosphorylated by the Pcl1p-Pho85p kinase complex; human homolog XAB1 interacts with human RNA polymerase II<ref name='S000145298'>Alonso B, et al. (2011) A role for GPN-loop GTPase yGPN1 in sister chromatid cohesion. Cell Cycle 10(11) {{SGDpaper|S000145298}} PMID 21532343</ref><ref name='S000076600'>Dez C, et al. (2004) Npa1p, a component of very early pre-60S ribosomal particles, associates with a subset of small nucleolar RNPs required for peptidyl transferase center modification. Mol Cell Biol 24(14):6324-37 {{SGDpaper|S000076600}} PMID 15226434</ref><ref name='S000146718'>Gras S, et al. (2007) Structural insights into a new homodimeric self-activated GTPase family. EMBO Rep 8(6):569-75 {{SGDpaper|S000146718}} PMID 17468740</ref><ref name='S000081511'>Keniry ME, et al. (2004) The identification of Pcl1-interacting proteins that genetically interact with Cla4 may indicate a link between G1 progression and mitotic exit. Genetics 166(3):1177-86 {{SGDpaper|S000081511}} PMID 15082539</ref><ref name='S000146392'>Staresincic L, et al. (2011) GTP-dependent binding and nuclear transport of RNA polymerase II by NPA3. J Biol Chem () |
| − | {{SGDpaper| | + | {{SGDpaper|S000146392}} PMID 21844196</ref> |
<br> | <br> | ||
<br> | <br> | ||
Latest revision as of 07:45, 23 January 2012
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| Systematic name | YJR072C |
| Gene name | NPA3 |
| Aliases | EPA1, GPN1 |
| Feature type | ORF, Verified |
| Coordinates | Chr X:572124..570967 |
| Primary SGDID | S000003833 |
Description of YJR072C: Member of the conserved GPN-loop GTPase family; has a role in transport of RNA polymerase II to the nucleus; exhibits GTP-dependent binding to PolII; has ATPase activity; involved in sister chromatid cohesion; phosphorylated by the Pcl1p-Pho85p kinase complex; human homolog XAB1 interacts with human RNA polymerase II[1][2][3][4][5]
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References
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- ↑ Alonso B, et al. (2011) A role for GPN-loop GTPase yGPN1 in sister chromatid cohesion. Cell Cycle 10(11) SGD PMID 21532343
- ↑ Dez C, et al. (2004) Npa1p, a component of very early pre-60S ribosomal particles, associates with a subset of small nucleolar RNPs required for peptidyl transferase center modification. Mol Cell Biol 24(14):6324-37 SGD PMID 15226434
- ↑ Gras S, et al. (2007) Structural insights into a new homodimeric self-activated GTPase family. EMBO Rep 8(6):569-75 SGD PMID 17468740
- ↑ Keniry ME, et al. (2004) The identification of Pcl1-interacting proteins that genetically interact with Cla4 may indicate a link between G1 progression and mitotic exit. Genetics 166(3):1177-86 SGD PMID 15082539
- ↑ Staresincic L, et al. (2011) GTP-dependent binding and nuclear transport of RNA polymerase II by NPA3. J Biol Chem () SGD PMID 21844196
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