YJR033C
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| Systematic name | YJR033C |
| Gene name | RAV1 |
| Aliases | SOI3 |
| Feature type | ORF, Verified |
| Coordinates | Chr X:496443..492370 |
| Primary SGDID | S000003794 |
Description of YJR033C: Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of the V-ATPase holoenzyme; required for transport between the early and late endosome/PVC and for localization of TGN membrane proteins; potential Cdc28p substrate[1][2][3][4][5]
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [3] [6]
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References
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- ↑ Smardon AM, et al. (2002) The RAVE complex is essential for stable assembly of the yeast V-ATPase. J Biol Chem 277(16):13831-9 SGD PMID 11844802
- ↑ Sipos G, et al. (2004) Soi3p/Rav1p functions at the early endosome to regulate endocytic trafficking to the vacuole and localization of trans-Golgi network transmembrane proteins. Mol Biol Cell 15(7):3196-209 SGD PMID 15090613
- ↑ 3.0 3.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ Seol JH, et al. (2001) Skp1 forms multiple protein complexes, including RAVE, a regulator of V-ATPase assembly. Nat Cell Biol 3(4):384-91 SGD PMID 11283612
- ↑ Redding K, et al. (1996) Allele-specific suppression of a defective trans-Golgi network (TGN) localization signal in Kex2p identifies three genes involved in localization of TGN transmembrane proteins. Mol Cell Biol 16(11):6208-17 SGD PMID 8887651
- ↑ submitted by Jeff Ubersax on 2004-01-27
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