Difference between revisions of "YJL143W"

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'''Description of YJL143W:''' Essential constituent of the mitochondrial inner membrane presequence translocase; interacts with Pam18p to recruit the presequence translocase-associated motor (PAM complex) and also required for protein sorting during import<ref name='S000081217'>Chacinska A, et al. (2005) Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17. Cell 120(6):817-29
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'''Description of YJL143W:''' Essential subunit of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); with Tim23p, contributes to the architecture and function of the import channel; may link the import motor to the core TIM23 complex<ref name='S000081217'>Chacinska A, et al. (2005) Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17. Cell 120(6):817-29 {{SGDpaper|S000081217}} PMID 15797382</ref><ref name='S000130845'>Martinez-Caballero S, et al. (2007) Tim17p regulates the twin pore structure and voltage gating of the mitochondrial protein import complex TIM23. J Biol Chem 282(6):3584-93
  {{SGDpaper|S000081217}} PMID 15797382</ref>
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  {{SGDpaper|S000130845}} PMID 17148445</ref>
 
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Revision as of 14:05, 4 August 2009

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Systematic name YJL143W
Gene name TIM17
Aliases MIM17, MPI2, SMS1
Feature type ORF, Verified
Coordinates Chr X:147097..147573
Primary SGDID S000003679


Description of YJL143W: Essential subunit of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); with Tim23p, contributes to the architecture and function of the import channel; may link the import motor to the core TIM23 complex[1][2]




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References

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  1. Chacinska A, et al. (2005) Mitochondrial presequence translocase: switching between TOM tethering and motor recruitment involves Tim21 and Tim17. Cell 120(6):817-29 SGD PMID 15797382
  2. Martinez-Caballero S, et al. (2007) Tim17p regulates the twin pore structure and voltage gating of the mitochondrial protein import complex TIM23. J Biol Chem 282(6):3584-93 SGD PMID 17148445

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