YJL092W
Share your knowledge...Edit this entry! <protect>
| Systematic name | YJL092W |
| Gene name | HPR5 |
| Aliases | RADH, RADH1, SRS2 |
| Feature type | ORF, Verified |
| Coordinates | Chr X:257418..260942 |
| Primary SGDID | S000003628 |
Description of YJL092W: DNA helicase and DNA-dependent ATPase involved in DNA repair, needed for proper timing of commitment to meiotic recombination and transition from Meiosis I to II; affects genome stability by suppressing unscheduled homologous recombination[1][2][3][4][5]
</protect>
Community Commentary
About Community Commentary. Please share your knowledge!
Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [2] [6]
<protect>
References
See Help:References on how to add references
- ↑ Papouli E, et al. (2005) Crosstalk between SUMO and ubiquitin on PCNA is mediated by recruitment of the helicase Srs2p. Mol Cell 19(1):123-33 SGD PMID 15989970
- ↑ 2.0 2.1 Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ Rong L and Klein HL (1993) Purification and characterization of the SRS2 DNA helicase of the yeast Saccharomyces cerevisiae. J Biol Chem 268(2):1252-9 SGD PMID 8419328
- ↑ Aboussekhra A, et al. (1989) RADH, a gene of Saccharomyces cerevisiae encoding a putative DNA helicase involved in DNA repair. Characteristics of radH mutants and sequence of the gene. Nucleic Acids Res 17(18):7211-9 SGD PMID 2552405
- ↑ Palladino F and Klein HL (1992) Analysis of mitotic and meiotic defects in Saccharomyces cerevisiae SRS2 DNA helicase mutants. Genetics 132(1):23-37 SGD PMID 1327956
- ↑ submitted by Jeff Ubersax on 2004-01-27
See Help:Categories on how to add the wiki page for this gene to a Category </protect>
