Difference between revisions of "YJL087C"

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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://db.yeastgenome.org/cgi-bin/locus.pl?locus=YJL087C YJL087C]  
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Systematic name''' || [http://www.yeastgenome.org/cgi-bin/locus.pl?dbid=S000003623 YJL087C]  
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''TRL1 ''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Gene name'''        ||''TRL1 ''
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
 
|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Coordinates'''
|nowrap| Chr X:272480..269997
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|nowrap| Chr X:272485..270002
 
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|valign="top" nowrap bgcolor="{{SGDblue}}"| '''Primary SGDID'''          || S000003623
 
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'''Description of {{PAGENAME}}:''' tRNA ligase, required for tRNA splicing; composed of three essential domains containing the phosphodiesterase, polynucleotide kinase, and ligase activities required for ligation; localized at the inner membrane of the nuclear envelope<ref name='S000057073'>Clark MW and Abelson J (1987) The subnuclear localization of tRNA ligase in yeast. J Cell Biol 105(4):1515-26 {{SGDpaper|S000057073}} PMID 3312232</ref><ref name='S000056811'>Xu Q, et al. (1990) Domain structure in yeast tRNA ligase. Biochemistry 29(26):6132-8
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'''Description of YJL087C:''' tRNA ligase, required for tRNA splicing and for both splicing and translation of HAC1 mRNA in the UPR; has phosphodiesterase, polynucleotide kinase, and ligase activities; localized at the inner nuclear envelope and partially to polysomes<ref name='S000057073'>Clark MW and Abelson J (1987) The subnuclear localization of tRNA ligase in yeast. J Cell Biol 105(4):1515-26 {{SGDpaper|S000057073}} PMID 3312232</ref><ref name='S000136483'>Mori T, et al. (2010) Dual Functions of Yeast tRNA Ligase in the Unfolded Protein Response: Unconventional Cytoplasmic Splicing of HAC1 Pre-mRNA Is Not Sufficient to Release Translational Attenuation. Mol Biol Cell 21(21):3722-34 {{SGDpaper|S000136483}} PMID 20844078</ref><ref name='S000056811'>Xu Q, et al. (1990) Domain structure in yeast tRNA ligase. Biochemistry 29(26):6132-8
 
  {{SGDpaper|S000056811}} PMID 2207062</ref>
 
  {{SGDpaper|S000056811}} PMID 2207062</ref>
 
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==Community Commentary==
 
==Community Commentary==
 
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Specifically higher expression in carbon limited chemostat cultures versus carbon excess.
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<ref>Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur.
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J Biol Chem 278(5):3265-74</ref>
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==References==
 
==References==
 
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Latest revision as of 07:45, 23 January 2012

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Systematic name YJL087C
Gene name TRL1
Aliases LIG1, RLG1
Feature type ORF, Verified
Coordinates Chr X:272485..270002
Primary SGDID S000003623


Description of YJL087C: tRNA ligase, required for tRNA splicing and for both splicing and translation of HAC1 mRNA in the UPR; has phosphodiesterase, polynucleotide kinase, and ligase activities; localized at the inner nuclear envelope and partially to polysomes[1][2][3]




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References

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  1. Clark MW and Abelson J (1987) The subnuclear localization of tRNA ligase in yeast. J Cell Biol 105(4):1515-26 SGD PMID 3312232
  2. Mori T, et al. (2010) Dual Functions of Yeast tRNA Ligase in the Unfolded Protein Response: Unconventional Cytoplasmic Splicing of HAC1 Pre-mRNA Is Not Sufficient to Release Translational Attenuation. Mol Biol Cell 21(21):3722-34 SGD PMID 20844078
  3. Xu Q, et al. (1990) Domain structure in yeast tRNA ligase. Biochemistry 29(26):6132-8 SGD PMID 2207062

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